ArticleActa neuropathologica1993
CD24, a signal-transducing molecule expressed on human B lymphocytes, is a marker for human regenerating muscle.
Article in Acta neuropathologica, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 59 citations in OpenAlex.
- HCNS neuroscience & therapeutics · 2025Article
- Myofiber Baf60c controls muscle regeneration by modulating Dkk3-mediated paracrine signaling.The Journal of experimental medicine · 2023Article
- Stem Cell Growth and Differentiation in Organ Culture: New Insights for Uterine Fibroid Treatment.Biomedicines · 2022Article
- Coding Cell Identity of Human Skeletal Muscle Progenitor Cells Using Cell Surface Markers: Current Status and Remaining Challenges for Characterization and Isolation.Frontiers in cell and developmental biology · 2019Review
- Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord-specific markers during early human intervertebral disc development.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2016Article
- CD24: from a Hematopoietic Differentiation Antigen to a Genetic Risk Factor for Multiple Autoimmune Diseases.Clinical reviews in allergy & immunology · 2016Review
- Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regeneration.The Journal of pathology · 2013Article
- A simple method to obtain pure cultures of multiciliated ependymal cells from adult rodents.Histochemistry and cell biology · 2013Article
- A critical re-evaluation of CD24-positivity of human embryonic stem cells differentiated into pancreatic progenitors.Stem cell reviews and reports · 2012Article
- Transcriptional profiling of bovine milk using RNA sequencing.BMC genomics · 2012Article
- CD24: from A to Z.Cellular & molecular immunology · 2010Review
- Regenerative potentials of the murine thyroid in experimental autoimmune thyroiditis: role of CD24.Endocrinology · 2009Article
- CD24 is expressed by myofiber synaptic nuclei and regulates synaptic transmission.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Article
- CD24 is an independent prognostic marker of survival in nonsmall cell lung cancer patients.British journal of cancer · 2003Article
- CD44H is expressed by cells of the oligodendrocyte lineage and by oligodendrogliomas in humans.Journal of neuro-oncology · 2002Article
- CD24 is expressed in ovarian cancer and is a new independent prognostic marker of patient survival.The American journal of pathology · 2002Article
- Increased neurogenesis in adult mCD24-deficient mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002Article
- Diagnostic protein expression in human muscle biopsies.Brain pathology (Zurich, Switzerland) · 2000Review
- The PEN5 epitope identifies an oligodendrocyte precursor cell population and pilocytic astrocytomas.The American journal of pathology · 1999Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The expression of the CD24 molecule, a glycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts, was studied in developing nerve and muscle (after 16 weeks of gestation), normal adult and various diseased human muscles using immunohistochemistry and Western blot analysis. Immunohistochemical studies demonstrated that: (1) in developing muscles, fibers did not express CD24, whereas only some mesenchymal areas, also expressing neural cell adhesion molecule (N.CAM) and vimentin, and developing nerves were positive; (2) in normal adult muscles, CD24 immunoreactivity was observed only in some unmyelinated nerve fibers--intra and extra fusal muscle fibers, satellite cells and neuromuscular junctions were negative; and (3) in all diseased muscles studied here, CD24 expression was always associated with a subpopulation of regenerative fibers. These fibers also expressed vimentin, desmin, developmental myosin heavy chain, N.CAM and its polysialylated isoforms (PSA-N.CAM). The number of CD24-positive fibers was always lower than that of PSA-N.CAM-positive fibers. Denervated fibers and vacuolated muscle fibers never expressed CD24. Western blot analysis indicated that the apparent molecular mass of CD24 antigen was different between muscle and developing nervous tissues, suggesting that CD24 glycosylation is tissue specific. Since the molecule was not expressed in developing human muscle fibers, it strongly suggests that regenerative and fetal myotubes are different with respect to the CD24 molecule expression.
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