ReviewProceedings of the National Academy of Sciences of the United States of America1994
Regulated vesicular fusion in neurons: snapping together the details.
Review in Proceedings of the National Academy of Sciences of the United States of America, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 90 citations in OpenAlex.
- KHSRP loss increases neuronal growth and synaptic transmission and alters memory consolidation through RNA stabilization.Communications biology · 2022Article
- Article
- Secretagogin is expressed in sensory CGRP neurons and in spinal cord of mouse and complements other calcium-binding proteins, with a note on rat and human.Molecular pain · 2012Article
- Termination and initial branch formation of SNAP-25-deficient thalamocortical fibres in heterochronic organotypic co-cultures.The European journal of neuroscience · 2012Article
- The role of the t-SNARE SNAP-25 in action potential-dependent calcium signaling and expression in GABAergic and glutamatergic neurons.BMC neuroscience · 2008Article
- Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
- The Tlg SNARE complex is required for TGN homotypic fusion.The Journal of cell biology · 2001Article
- Cysteine residues of SNAP-25 are required for SNARE disassembly and exocytosis, but not for membrane targeting.The Biochemical journal · 2001Article
- A single amino acid near the C terminus of the synaptosomeassociated protein of 25 kDa (SNAP-25) is essential for exocytosis in chromaffin cells.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- SNAP-25a and -25b isoforms are both expressed in insulin-secreting cells and can function in insulin secretion.The Biochemical journal · 1999Article
- Molecular diversity in neurosecretion: reflections on the hypothalamo-neurohypophysial system.Cellular and molecular neurobiology · 1998Review
- SNAP-25 palmitoylation and plasma membrane targeting require a functional secretory pathway.Molecular biology of the cell · 1998Article
- The soluble N-ethylmaleimide-sensitive factor attached protein receptor complex in growth cones: molecular aspects of the axon terminal development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1997Article
- SNAP-25 and synaptotagmin involvement in the final Ca(2+)-dependent triggering of neurotransmitter exocytosis.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2.The Biochemical journal · 1996Article
- Growth cone collapse and inhibition of neurite growth by Botulinum neurotoxin C1: a t-SNARE is involved in axonal growth.The Journal of cell biology · 1996Article
- Mouse model of hyperkinesis implicates SNAP-25 in behavioral regulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1996Article
- An Arabidopsis syntaxin homologue isolated by functional complementation of a yeast pep12 mutant.Proceedings of the National Academy of Sciences of the United States of America · 1995Article
- Differential expression of SNAP-25 protein isoforms during divergent vesicle fusion events of neural development.Proceedings of the National Academy of Sciences of the United States of America · 1995Article
- Immediate upstream promoter regions required for neurospecific expression of SNAP-25.Journal of molecular neuroscience : MN · 1995Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In the past year major strides have been made toward our understanding of the molecular mechanisms involved in regulated vesicle fusion and exocytosis in neurons and neuroendocrine cells. Much of this advance has come from the identification of proteins participating in these events and of their potential roles mediated by interactions with each other, the constituent membranes, and, in some cases, Ca2+ signaling. The involvement of vesicle fusion in elongation of neuronal processes during development and release of transmitters and neuromodulatory peptides in the mature nervous system indicates, however, that refinements in the fusion machinery may be required for each of these acts. For many of the participants in synaptic membrane fusion, variant isoforms have been identified that exhibit modifications that might alter interactive properties of these proteins. We discuss the idea that diversification of isoforms, as illustrated by the expression of alternatively spliced variants of SNAP-25, is likely to be an important component in providing the detail necessary to differentiate the physiology of regulated fusion of different classes of vesicles employed in development, neurotransmission, and secretion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.