Evidence map›Paper›PMID 8194579›Full record

ArticleExperientia1994

Regulation of the retinal interphotoreceptor matrix Na by the retinal pigment epithelium during the light response.

S Hodson, I Armstrong, C Wigham

Abstract read
PubMed Publisher
In one paragraph

Article in Experientia, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. OCT imaging of rod mitochondrial respirationExperimental biology and medicine (Maywood, N.J.) · 2021
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

S HodsonDepartment of Optometry and Vision Sciences, UWC Cardiff, Great Britain.
I Armstrong
C Wigham

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We examined the rabbit retinal pigment epithelium (RPE) for Na transport properties which would allow it to buffer undesirable changes in Na concentrations in the interphotoreceptor matrix (IPM) during light and dark cycles. The RPE is selectivity permeable to sodium. Open and short circuit transport studies with RPE indicate a circulating (choroid to retina and back) Na current which does not compromise the electrical integrity of the blood brain barrier but together with the Na permselectivity is of sufficient magnitude to buffer both upwards and downwards movements of IPM [Na] during light or dark responses.

Indexed as

AnimalsBicarbonatesCell Membrane PermeabilityChloridesChoroidDarknessIn Vitro TechniquesLightMembrane PotentialsPhotoreceptor CellsPigment Epithelium of EyePotentiometryRabbitsScleraSodiumSodium ChannelsBicarbonatesChloridesSodiumSodium Channels

Identifiers

PMID8194579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.