ArticleMolecular & general genetics : MGG1994
Intron loss from the NADH dehydrogenase subunit 4 gene of lettuce mitochondrial DNA: evidence for homologous recombination of a cDNA intermediate.
Article in Molecular & general genetics : MGG, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 54 citations in OpenAlex.
- The dual-targeted RNA editing factor AEF1 is universally conserved among angiosperms and reveals only minor adaptations upon loss of its chloroplast or its mitochondrial target.Plant molecular biology · 2020Article
- Potential of Transcript Editing Across Mitogenomes of Early Land Plants Shows Novel and Familiar Trends.International journal of molecular sciences · 2019Article
- Towards a comprehensive picture of C-to-U RNA editing sites in angiosperm mitochondria.Plant molecular biology · 2018Article
- Article
- Mitochondrial Retroprocessing Promoted Functional Transfers of rpl5 to the Nucleus in Grasses.Molecular biology and evolution · 2017Article
- Convergent Evolution of Fern-Specific Mitochondrial Group II Intron atp1i361g2 and Its Ancient Source Paralogue rps3i249g2 and Independent Losses of Intron and RNA Editing among Pteridaceae.Genome biology and evolution · 2016Article
- Localized Retroprocessing as a Model of Intron Loss in the Plant Mitochondrial Genome.Genome biology and evolution · 2016Article
- Chloroplast RNA editing going extreme: more than 3400 events of C-to-U editing in the chloroplast transcriptome of the lycophyte Selaginella uncinata.RNA (New York, N.Y.) · 2014Article
- Genes and processed paralogs co-exist in plant mitochondria.Journal of molecular evolution · 2012Article
- Article
- Frequent, phylogenetically local horizontal transfer of the cox1 group I Intron in flowering plant mitochondria.Molecular biology and evolution · 2008Article
- Recurrent invasion of mitochondrial group II introns in specimens of Pylaiella littoralis (brown alga), collected worldwide.Current genetics · 2008Article
- An Arabidopsis homologue of bacterial RecA that complements an E. coli recA deletion is targeted to plant mitochondria.Molecular genetics and genomics : MGG · 2003Article
- RNA editing in gymnosperms and its impact on the evolution of the mitochondrial coxI gene.Plant molecular biology · 1998Article
- Distribution and evolution of introns in Drosophila amylase genes.Journal of molecular evolution · 1996Article
- RNA editing in plant mitochondria and chloroplasts.Plant molecular biology · 1996Review
- Characterization of the radish mitochondrial nad3/rps12 locus: analysis of recombination repeats and RNA editing.Current genetics · 1996Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mitochondrial gene coding for subunit 4 of the NADH dehydrogenase complex I (nad4) has been isolated and characterized from lettuce, Lactuca sativa. Analysis of nad4 genes in a number of plants by Southern hybridization had previously suggested that the intron content varied between species. Characterization of the lettuce gene confirms this observation. Lettuce nad4 contains two exons and one group IIA intron, whereas previously sequenced nad4 genes from turnip and wheat contain three group IIA introns. Northern analysis identified a transcript of 1600 nucleotides, which represents the mature nad4 mRNA and a primary transcript of 3200 nucleotides. Sequence analysis of lettuce and turnip nad4 cDNAs was used to confirm the intron/exon border sequences and to examine RNA editing patterns. Editing is observed at the 5' and 3' ends of the lettuce transcript, but is absent from sequences that correspond to exons two, three and the 5' end of exon four in turnip and wheat. In contrast, turnip transcripts are highly edited in this region, suggesting that homologous recombination of an edited and spliced cDNA intermediate was involved in the loss of introns two and three from an ancestral lettuce nad4 gene.
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