ReviewMolecular neurobiology
Development of trophic interactions in the vertebrate peripheral nervous system.
Review in Molecular neurobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 31 citations in OpenAlex.
- Calcitonin gene-related peptide in the joint: contributions to pain and inflammation.British journal of clinical pharmacology · 2015Review
- Neuroprotection signaling of nuclear akt in neuronal cells.Experimental neurobiology · 2014Review
- Factors that regulate embryonic gustatory development.BMC neuroscience · 2007Review
- Differential Trk expression in explant and dissociated trigeminal ganglion cell cultures.Journal of neurobiology · 2005Article
- Target specific differentiation of peripheral trigeminal axons in rat-chick chimeric explant cocultures.Brain research. Developmental brain research · 2001Article
- A sensory neuron subpopulation with unique sequential survival dependence on nerve growth factor and basic fibroblast growth factor during development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001Article
- Experimental cisplatin neuronopathy in rats and the effect of retinoic acid administration.Journal of neuro-oncology · 1998Article
- Trk receptors function as rapid retrograde signal carriers in the adult nervous system.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1997Article
- TrkA, but not TrkC, receptors are essential for survival of sympathetic neurons in vivo.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1996Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During embryogenesis, the neurons of vertebrate sympathetic and sensory ganglia become dependent on neurotrophic factors, derived from their targets, for survival and maintenance of differentiated functions. Many of these interactions are mediated by the neurotrophins NGF, BDNF, and NT3 and the receptor tyrosine kinases encoded by genes of the trk family. Both sympathetic and sensory neurons undergo developmental changes in their responsiveness to NGF, the first neurotrophin to be identified and characterized. Subpopulations of sensory neurons do not require NGF for survival, but respond instead to BDNF or NT3 with enhanced survival. In addition to their classic effects on neuron survival, neurotrophins influence the differentiation and proliferation of neural crest-derived neuronal precursors. In both sympathetic and sensory systems, production of neurotrophins by target cells and expression of neurotrophin receptors by neurons are correlated temporally and spatially with innervation patterns. In vitro, embryonic sympathetic neurons require exposure to environmental cues, such as basic FGF and retinoic acid to acquire neurotrophin-responsiveness; in contrast, embryonic sensory neurons acquire neurotrophin-responsiveness on schedule in the absence of these molecules.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.