ArticleThe American journal of pathology1994
Characterization of cloned aortic smooth muscle cells from young rats.
Article in The American journal of pathology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 122 citations in OpenAlex.
- Guidelines for the isolation and characterization of murine vascular smooth muscle cells. A report from the International Society of Cardiovascular Translational Research.Journal of cardiovascular translational research · 2015Guideline
- V3: an enigmatic isoform of the proteoglycan versican.American journal of physiology. Cell physiology · 2023Review
- Vascular Smooth Muscle Cell Subpopulations and Neointimal Formation in Mouse Models of Elastin Insufficiency.Arteriosclerosis, thrombosis, and vascular biology · 2021Article
- Premature aortic smooth muscle cell differentiation contributes to matrix dysregulation in Marfan Syndrome.PloS one · 2017Article
- Intimal smooth muscle cells are a source but not a sensor of anti-inflammatory CYP450 derived oxylipins.Biochemical and biophysical research communications · 2015Article
- Self-assembled smooth muscle cell tissue rings exhibit greater tensile strength than cell-seeded fibrin or collagen gel rings.Journal of biomedical materials research. Part A · 2013Article
- Differentiation of multipotent vascular stem cells contributes to vascular diseases.Nature communications · 2012Article
- Article
- Engineered vascular tissue fabricated from aggregated smooth muscle cells.Cells, tissues, organs · 2011Article
- Expression of versican isoform V3 in the absence of ascorbate improves elastogenesis in engineered vascular constructs.Tissue engineering. Part A · 2010Article
- Angiotensin II induction of PDGF-C expression is mediated by AT1 receptor-dependent Egr-1 transactivation.Nucleic acids research · 2008Article
- Peroxide-inducible Ets-1 mediates platelet-derived growth factor receptor-alpha gene transcription in vascular smooth muscle cells.The American journal of pathology · 2005Article
- Cell volume and rate of proliferation, but not protein expression pattern, distinguish pup/intimal smooth muscle cells from subcultured adult smooth muscle cells.Cell proliferation · 2001Article
- Sp1 phosphorylation regulates inducible expression of platelet-derived growth factor B-chain gene via atypical protein kinase C-zeta.Nucleic acids research · 2001Article
- Mechanisms of angiotensin II-induced platelet-derived growth factor gene expression.Molecular and cellular biochemistry · 2000Review
- Enhanced H(2)O(2)-induced cytotoxicity in "epithelioid" smooth muscle cells: implications for neointimal regression.Arteriosclerosis, thrombosis, and vascular biology · 2000Article
- The clonal origin and clonal evolution of epithelial tumours.International journal of experimental pathology · 2000Review
- Vessel size-dependent expression of intermediate-sized filaments, calponin, and h-caldesmon in smooth muscle cells of human coronary arteries.Heart and vessels · 1999Article
- Clonal architecture of normal and atherosclerotic aorta: implications for atherogenesis and vascular development.The American journal of pathology · 1998Article
- A comparative molecular analysis of four rat smooth muscle cell lines.In vitro cellular & developmental biology. Animal · 1998Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Clones were derived by dilute plating from cultured aortic smooth muscle cells of 12-day-old rats. Clones Pup I to III resemble uncloned smooth muscle cultures from aortas of rat pups and from adult rat neointimas. They have a cobblestone morphology and proliferate in plasma-derived serum. By Northern analysis they contain platelet-derived growth factor B chain (PDGF-B) mRNA and high levels of CYPIA1, elastin, and osteopontin mRNAs, and they lack platelet-derived growth factor alpha-receptor (PDGF-alpha R) mRNA. In contrast, Pup V resembles smooth muscle cultures derived from uninjured adult rat arteries. It has an elongated morphology and proliferates poorly in plasma-derived serum. This clone expresses PDGF-alpha R mRNA, low levels of elastin and osteopontin mRNAs, and lacks CYPIA1 and PDGF-B mRNAs. Pup IV and VI have most of the properties of Pup I to III. We conclude that uncloned pup cultures are heterogeneous, but that the growth properties and gene expression pattern described for the uncloned culture is characteristic of individual clones within the population.
Indexed as
Identifiers
8178930PMC1887366W2296950434What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.