ArticleProceedings of the National Academy of Sciences of the United States of America1994
Genetic analysis of the NZB contribution to lupus-like autoimmune disease in (NZB x NZW)F1 mice.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 168 citations in OpenAlex.
- An Lck-cre transgene accelerates autoantibody production and lupus development in (NZB × NZW)F1 mice.Lupus · 2016Article
- Chance, genetics, and the heterogeneity of disease and pathogenesis in systemic lupus erythematosus.Seminars in immunopathology · 2014Review
- Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus.Arthritis and rheumatism · 2010Article
- Estrogen receptor-alpha deficiency attenuates autoimmune disease in (NZB x NZW)F1 mice.Genes and immunity · 2008Article
- Current topics in human SLE genetics.Springer seminars in immunopathology · 2006Review
- Genes mediating environment interactions in type 1 diabetes.The review of diabetic studies : RDS · 2005Article
- Multiple loci are linked with anti-red blood cell antibody production in NZB mice -- comparison with other phenotypes implies complex modes of action.Clinical and experimental immunology · 2004Article
- The candidate gene approach: have murine models informed the study of human SLE?Clinical and experimental immunology · 2004Review
- Dominant NZB contributions to lupus in the (SWR x NZB)F1 model.Genes and immunity · 2002Article
- The genetics of systemic lupus erythematosus: putting the pieces together.Genes and immunity · 2002Review
- Evidence for a susceptibility gene (SLEH1) on chromosome 11q14 for systemic lupus erythematosus (SLE) families with hemolytic anemia.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Calorie restriction decreases proinflammatory cytokines and polymeric Ig receptor expression in the submandibular glands of autoimmune prone (NZB x NZW)F1 mice.Journal of clinical immunology · 2000Article
- Involvement of Sp1 and microsatellite repressor sequences in the transcriptional control of the human CD30 gene.The American journal of pathology · 2000Article
- Genetic studies in systemic autoimmunity and aging.Immunologic research · 2000Review
- Control of separate pathogenic autoantibody responses marks MHC gene contributions to murine lupus.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies.The Journal of experimental medicine · 1999Article
- A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Immune cell signaling aberrations in human lupus.Immunologic research · 1998Review
- Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.The Journal of clinical investigation · 1998Article
- Genetic dissection of lupus nephritis in murine models of SLE.Journal of clinical immunology · 1997Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Lupus-like autoimmunity in (NZB x NZW)F1 mice is frequently marked by the development of a severe and fatal renal disease. Genes from both NZB and NZW parents are required for the full expression of disease. We applied a mapping technique based on polymorphism in simple sequence repeats to the analysis of (NZB x NZW)F1 x NZW backcross mice to determine the NZB genetic contribution to disease. The results show that a single NZB locus or tightly linked group of loci on the distal part of chromosome 4 provides the strongest association with renal disease and death. This locus, designated here as nba-1 (New Zealand Black autoimmunity), lies distal to the locus elp-1, 60-70 centimorgans from the centromere. It is of interest that a gene encoding a receptor for tumor necrosis factor maps to the vicinity of this disease-associated gene.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.