ArticleProceedings of the National Academy of Sciences of the United States of America1994
Inhibition of inward K+ channels and stomatal response by abscisic acid: an intracellular locus of phytohormone action.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
50 citing papers in PubMed, 164 citations in OpenAlex.
- Guard cell signal transduction mechanisms controlling stomatal movements by light, abscisic acid, CO2, VPD and heat.Plant physiology · 2026Review
- ABA receptor isoforms differently regulate stomatal movements and generation of reactive oxygen species in ABA signaling in Arabidopsis guard cells.Plant & cell physiology · 2025Article
- Integrated physiological, transcriptomic, and metabolomic analyses ofFrontiers in plant science · 2025Article
- Calcium-dependent protein kinase CPK9 negatively functions in stomatal abscisic acid signaling by regulating ion channel activity in Arabidopsis.Plant molecular biology · 2019Article
- Blue light and CONature communications · 2017Article
- Arabidopsis CALCIUM-DEPENDENT PROTEIN KINASE8 and CATALASE3 Function in Abscisic Acid-Mediated Signaling and H2O2 Homeostasis in Stomatal Guard Cells under Drought Stress.The Plant cell · 2015Article
- Elevated air movement enhances stomatal sensitivity to abscisic acid in leaves developed at high relative air humidity.Frontiers in plant science · 2015Article
- The guard cell metabolome: functions in stomatal movement and global food security.Frontiers in plant science · 2015Review
- Difference in abscisic acid perception mechanisms between closure induction and opening inhibition of stomata.Plant physiology · 2013Article
- Abscisic Acid synthesis and response.The arabidopsis book · 2013Article
- FIA functions as an early signal component of abscisic acid signal cascade in Vicia faba guard cells.Journal of experimental botany · 2012Article
- Transport of ABA from the site of biosynthesis to the site of action.Journal of plant research · 2011Review
- ABA signaling in stomatal guard cells: lessons from Commelina and Vicia.Journal of plant research · 2011Review
- Structural insights into maize viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid.The Plant cell · 2010Article
- Early abscisic acid signal transduction mechanisms: newly discovered components and newly emerging questions.Genes & development · 2010Review
- PDR-type ABC transporter mediates cellular uptake of the phytohormone abscisic acid.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Host cell autophagy is induced by Toxoplasma gondii and contributes to parasite growth.The Journal of biological chemistry · 2009Article
- Functional proteomics of Arabidopsis thaliana guard cells uncovers new stomatal signaling pathways.The Plant cell · 2008Article
- Ggamma1 + Ggamma2 not equal to Gbeta: heterotrimeric G protein Ggamma-deficient mutants do not recapitulate all phenotypes of Gbeta-deficient mutants.Plant physiology · 2008Article
- Transient expression of AtNCED3 and AAO3 genes in guard cells causes stomatal closure in Vicia faba.Journal of plant research · 2008Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abscisic acid (ABA), a plant hormone whose production is stimulated by water stress, reduces the apertures of stomatal pores in the leaf surface, thereby lessening transpirational water loss. It has been thought that inhibition of stomatal opening and promotion of stomatal closure by ABA are initiated by the binding of extracellular ABA to a receptor located in the guard-cell plasma membrane. However, in the present research, we employ three distinct experimental approaches to demonstrate that ABA can act from within guard cells to regulate stomatal apertures. (i) The extent to which ABA inhibits stomatal opening and promotes stomatal closure in Commelina communis L. is proportional to the extent of ABA uptake, as assayed with [3H]ABA. (ii) Direct microinjection of ABA into the cytoplasm of Commelina guard cells precipitates stomatal closure. (iii) Application of ABA to the cytosol of Vicia faba L. guard-cell protoplasts via patch-clamp techniques inhibits inward K+ currents, an effect sufficient to inhibit stomatal opening. These results demonstrate an intracellular locus of phytohormone action and imply that the search for hormone receptor proteins should be extended to include intracellular compartments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.