ArticleIn vitro cellular & developmental biology. Animal1993
Inhibition of cell growth by bafilomycin A1, a selective inhibitor of vacuolar H(+)-ATPase.
Article in In vitro cellular & developmental biology. Animal, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 50 citations in OpenAlex.
- Elimination of apoptotic cells by non-professional embryonic phagocytes can be stimulated or inhibited by external stimuli.Scientific reports · 2025Article
- 3DEmerging microbes & infections · 2022Article
- Unraveling and targeting RAS-driven metabolic signaling for therapeutic gain.Advances in cancer research · 2022Review
- Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors.Scientific reports · 2021Article
- The HAmerican journal of physiology. Cell physiology · 2021Review
- The viral protein U (Vpu)-interacting host protein ATP6V0C down-regulates cell-surface expression of tetherin and thereby contributes to HIV-1 release.The Journal of biological chemistry · 2020Article
- Iron-Doping of Copper Oxide Nanoparticles Lowers Their Toxic Potential on C6 Glioma Cells.Neurochemical research · 2020Article
- Differential Effects of Rapamycin and Metformin in Combination With Rapamycin on Mechanisms of Proteostasis in Cultured Skeletal Myotubes.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells.Oncotarget · 2017Article
- Autophagy Regulates Proteasome Inhibitor-Induced Pigmentation in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells.International journal of molecular sciences · 2017Article
- Identification of V-ATPase as a molecular sensor of SOX11-levels and potential therapeutic target for mantle cell lymphoma.BMC cancer · 2016Article
- Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia.Haematologica · 2015Article
- Undecylprodigiosin induced apoptosis in P388 cancer cells is associated with its binding to ribosome.PloS one · 2013Article
- Pyk2 regulates H+-ATPase-mediated proton secretion in the outer medullary collecting duct via an ERK1/2 signaling pathway.American journal of physiology. Renal physiology · 2012Article
- Low-pH triggering of human metapneumovirus fusion: essential residues and importance in entry.Journal of virology · 2009Article
- The proton pump inhibitor inhibits cell growth and induces apoptosis in human hepatoblastoma.Pediatric surgery international · 2008Article
- Bafilomycin A1 is a potassium ionophore that impairs mitochondrial functions.Journal of bioenergetics and biomembranes · 2007Article
- Poly(2-alkylacrylic acid) polymers deliver molecules to the cytosol by pH-sensitive disruption of endosomal vesicles.The Biochemical journal · 2003Article
- Infectious entry by amphotropic as well as ecotropic murine leukemia viruses occurs through an endocytic pathway.Journal of virology · 2001Article
- Bafilomycin A1 and intracellular multiplication of Legionella pneumophila.Antimicrobial agents and chemotherapy · 1997Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bafilomycin A1, a potent selective inhibitor of vacuolar H(+)-ATPase, inhibited the growth of a variety of cultured cells dose-dependently, including golden hamster embryo and NIH-3T3 fibroblasts, whether or not they were transformed, and PC12 and HeLa cells. The concentration of bafilomycin A1 for 50% inhibition of cell growth ranged from 10 to 50 nM. The dose response was nearly parallel with that of the bafilomycin A1-induced lysosomal pH increase. The degree of pH increase for growth inhibition produced by bafilomycin A1 was similar to that produced by NH4Cl in which little difference was recognized in effect among cell types.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.