Evidence map›Paper›PMID 8161707›Full record

ArticleBiophysical journal1994

Slow Na+ channel inactivation must be disrupted to evoke prolonged depolarization-induced paralysis.

R L Ruff

Abstract readCommentLetter
In one paragraph

Article in Biophysical journal, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Sodium Channelopathies of Skeletal Muscle.Handbook of experimental pharmacology · 2018
    Review
  5. Article
  6. Channelopathies of skeletal muscle excitability.Comprehensive Physiology · 2015
    Review
  7. Article
  8. Article
  9. Article
  10. Genotype-phenotype correlation and therapeutic rationale in hyperkalemic periodic paralysis.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2007
    Review
  11. Inherited disorders of voltage-gated sodium channels.The Journal of clinical investigation · 2005
    Review
  12. Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004
    Article
  13. The human skeletal muscle Na channel mutation R669H associated with hypokalemic periodic paralysis enhances slow inactivation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Alterations of Na+ channel gating in myotonia.The Journal of physiology · 1997
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

R L Ruff

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Sodium Channel BlockersAnimalsBiophysical PhenomenaBiophysicsHumansMembrane PotentialsModels, BiologicalMyotoniaParalysisSodium Channel Blockers

Identifiers

PMID8161707
PMCPMC1275721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.