ArticleMathematical biosciences1994
A G protein-based model of adaptation in Dictyostelium discoideum.
Article in Mathematical biosciences, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Multiscale phenomena and patterns in biological systems: special issue in honour of Hans Othmer.Journal of mathematical biology · 2020Article
- Fold-change detection and scale invariance of cell-cell signaling in social amoeba.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- A Model for Direction Sensing in Dictyostelium discoideum: Ras Activity and Symmetry Breaking Driven by a Gβγ-Mediated, Gα2-Ric8 -- Dependent Signal Transduction Network.PLoS computational biology · 2016Article
- Excitable waves and direction-sensing in Dictyostelium discoideum: steps towards a chemotaxis model.Physical biology · 2016Article
- Evolutionarily conserved coupling of adaptive and excitable networks mediates eukaryotic chemotaxis.Nature communications · 2014Article
- The Neurospora photoreceptor VIVID exerts negative and positive control on light sensing to achieve adaptation.Molecular systems biology · 2013Article
- Excitation and adaptation in bacteria-a model signal transduction system that controls taxis and spatial pattern formation.International journal of molecular sciences · 2013Article
- Modeling and measuring signal relay in noisy directed migration of cell groups.PLoS computational biology · 2013Article
- Spatial turing-type pattern formation in a model of signal transduction involving membrane-based receptors coupled by g proteins.Cancer informatics · 2007Article
- Taxis equations for amoeboid cells.Journal of mathematical biology · 2007Article
- A model for the pulsatile secretion of gonadotropin-releasing hormone from synchronized hypothalamic neurons.Biophysical journal · 2006Article
- Singular perturbation analysis of cAMP signalling in Dictyostelium discoideum aggregates.Journal of mathematical biology · 2006Article
- Mathematically modelling the effects of counting factor in Dictyostelium discoideum.Mathematical medicine and biology : a journal of the IMA · 2006Article
- Kinetic models for chemotaxis: hydrodynamic limits and spatio-temporal mechanisms.Journal of mathematical biology · 2005Article
- How cellular movement determines the collective force generated by the Dictyostelium discoideum slug.Journal of theoretical biology · 2004Article
- Models of eukaryotic gradient sensing: application to chemotaxis of amoebae and neutrophils.Biophysical journal · 2002Article
- cAMP signaling in Dictyostelium. Complexity of cAMP synthesis, degradation and detection.Journal of muscle research and cell motility · 2002Review
- Modeling chemotactic cell sorting during Dictyostelium discoideum mound formation.Biophysical journal · 1999Article
- A discrete cell model with adaptive signalling for aggregation of Dictyostelium discoideum.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 1997Article
- Positive genetic feedback governs cAMP spiral wave formation in Dictyostelium.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
Corrections and comments
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2 authors.
Funding
Abstract
A new model is proposed based on signal transduction via G proteins for adaptation of the signal relay process in the cellular slime mold Dictyostelium discoideum. The kinetic constants involved in the model are estimated from Dictyostelium discoideum and other systems. A qualitative analysis of the model shows how adaptation arises, and numerical computations show that the model agrees with observations in both perfusion and suspension experiments. Several experiments that can serve to test the model are suggested.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.