ArticleDiabetologia1994
A high weight gain early in life is associated with an increased risk of type 1 (insulin-dependent) diabetes mellitus.
Article in Diabetologia, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Increasing plasma glucose before the development of type 1 diabetes-the TRIGR study.Pediatric diabetes · 2021Trial
- Association between family history, early growth and the risk of beta cell autoimmunity in children at risk for type 1 diabetes.Diabetologia · 2021Trial
- Physical Activity, Blood Glucose and C-Peptide in Healthy School-Children, a Longitudinal Study.PloS one · 2016Trial
- The rise and fall of a paradigm and conceiving a new hypothesis for type 1 diabetes. Reply to Nerup J, Lernmark A [letter].Diabetologia · 2026Article
- Gestational diabetes and parental type 2 diabetes as risk indicators for type 1 diabetes in offspring: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- High-fat diet prevents the development of autoimmune diabetes in NOD mice.Diabetes, obesity & metabolism · 2021Article
- Growth and development of islet autoimmunity and type 1 diabetes in children genetically at risk.Diabetologia · 2021Article
- Nutrition and Obesity in the Pathogenesis of Youth-Onset Type 1 Diabetes and Its Complications.Frontiers in endocrinology · 2021Review
- Skeletal growth and bone mineral acquisition in type 1 diabetic children; abnormalities of the GH/IGF-1 axis.Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 2017Review
- Environmental risk factors for type 1 diabetes.Lancet (London, England) · 2016Review
- Article
- Is autoimmunity or insulin resistance the primary driver of type 1 diabetes?Current diabetes reports · 2013Review
- Connecting type 1 and type 2 diabetes through innate immunity.Cold Spring Harbor perspectives in medicine · 2012Review
- Height growth velocity, islet autoimmunity and type 1 diabetes development: the Diabetes Autoimmunity Study in the Young.Diabetologia · 2009Article
- Childhood BMI trajectories and the risk of developing young adult-onset diabetes.Diabetologia · 2009Article
- Children developing type 1 diabetes before 6 years of age have increased linear growth independent of HLA genotypes.Diabetologia · 2008Article
- Association analysis of the IGF1 gene with childhood growth, IGF-1 concentrations and type 1 diabetes.Diabetologia · 2008Article
- A population-specific diabetogenic haplotype HLA-A2,Cw1,B56,DR4,DQ8 is associated with high birthweight in Finnish diabetic families.Genes and immunity · 2008Article
- The effect of birth order and parental age on the risk of type 1 and 2 diabetes among young adults.Diabetologia · 2007Article
- Adiponectin levels do not predict clinical onset of type 1 diabetes in antibody-positive relatives.Diabetologia · 2007Article
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Abstract
Growth during the first years of life in relation to type of feeding in infancy was retrospectively studied in an unselected population-based group of 297 children who had been diagnosed with Type 1 (insulin-dependent) diabetes mellitus before the age of 15 years (probands) and 792 individually-matched referent subjects. Reliable data were collected from child welfare clinics. Probands weighed slightly less at birth but their weight gain at 6, 9, 18 and 30 months of age was significantly greater (p < 0.02) than that of referent children. The weight gain of children who had never been breast-fed was more marked than that of breast-fed children; this was found for both probands and referent children. But also among exclusively breast-fed children (> 2 months), probands gained significantly more in weight from birth up to 18 and 30 months of age than exclusively breast-fed referent children. Early weight gain appears to be a risk factor for development of Type 1 diabetes. The lower weight gain in breast-fed compared to non-breast-fed children may explain the protective effect of breast feeding against Type 1 diabetes observed in several studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.