Evidence map›Paper›PMID 8147264›Full record

ArticleAgents and actions1993

The effect of a cyclooxygenase inhibitor on the in vivo polymorphonuclear leukocyte migration to Pseudomonas aeruginosa peptide chemotactins.

P A Fontán, C R Amura, D O Sordelli

Abstract read
PubMed Publisher
In one paragraph

Article in Agents and actions, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

P A FontánDepartamento de Microbiología, Parasitología and Immunología, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
C R Amura
D O Sordelli
University of Buenos Aires · ARGeorgetown University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudomonas aeruginosa chemotactic peptides (PAPCs) induced migration of polymorphonuclear leukocytes (PMNL) into the lungs when administered by the aerosol route. Migration of PMNL into the lungs and total protein content of lung lavage fluids in response to PAPCs aerosol challenge, and mortality from lethal challenge with P. aeruginosa were decreased by piroxicam treatment.

Indexed as

AerosolsAnimalsBronchoalveolar Lavage FluidChemotactic FactorsChemotaxis, LeukocyteCulture MediaCyclooxygenase InhibitorsLungMiceNeutrophilsN-Formylmethionine Leucyl-PhenylalaninePiroxicamPseudomonas aeruginosaAerosolsChemotactic FactorsCulture MediaCyclooxygenase InhibitorsN-Formylmethionine Leucyl-PhenylalaninePiroxicam

Identifiers

PMID8147264
OpenAlexW1978185277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.