ArticleJournal of bacteriology1994
Evidence that asgB encodes a DNA-binding protein essential for growth and development of Myxococcus xanthus.
Article in Journal of bacteriology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed.
- Identifying the Gene Regulatory Network of the Starvation-Induced Transcriptional Activator Nla28.Journal of bacteriology · 2022Article
- Transcription factor MrpC binds to promoter regions of hundreds of developmentally-regulated genes in Myxococcus xanthus.BMC genomics · 2014Article
- Phenotypic profiling of ABC transporter coding genes in Myxococcus xanthus.Frontiers in microbiology · 2014Article
- Fatty acids from membrane lipids become incorporated into lipid bodies during Myxococcus xanthus differentiation.PloS one · 2014Article
- Phase variation in Myxococcus xanthus yields cells specialized for iron sequestration.PloS one · 2014Article
- A Myxococcus xanthus bacterial tyrosine kinase, BtkA, is required for the formation of mature spores.Journal of bacteriology · 2011Article
- Global analysis of phase variation in Myxococcus xanthus.Molecular microbiology · 2011Article
- Enzymatic and mutational analyses of a class II 3',5'-cyclic nucleotide phosphodiesterase, PdeE, from Myxococcus xanthus.Journal of bacteriology · 2011Article
- Heterologous expression of the oxytetracycline biosynthetic pathway in Myxococcus xanthus.Applied and environmental microbiology · 2010Article
- Glycine betaine biosynthesized from glycine provides an osmolyte for cell growth and spore germination during osmotic stress in Myxococcus xanthus.Journal of bacteriology · 2010Article
- Chemotaxis as an emergent property of a swarm.Journal of bacteriology · 2008Article
- Nla18, a key regulatory protein required for normal growth and development of Myxococcus xanthus.Journal of bacteriology · 2006Article
- Contribution of the cyclic nucleotide phosphodiesterases PdeA and PdeB to adaptation of Myxococcus xanthus cells to osmotic or high-temperature stress.Journal of bacteriology · 2006Article
- RasA is required for Myxococcus xanthus development and social motility.Journal of bacteriology · 2005Article
- An adenylyl cyclase, CyaB, acts as an osmosensor in Myxococcus xanthus.Journal of bacteriology · 2005Article
- nsd, a locus that affects the Myxococcus xanthus cellular response to nutrient concentration.Journal of bacteriology · 2004Article
- Global mutational analysis of NtrC-like activators in Myxococcus xanthus: identifying activator mutants defective for motility and fruiting body development.Journal of bacteriology · 2003Article
- act operon control of developmental gene expression in Myxococcus xanthus.Journal of bacteriology · 2002Article
- Mob psychology.Journal of bacteriology · 2002Review
- Control of asgE expression during growth and development of Myxococcus xanthus.Journal of bacteriology · 2000Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The asg mutants of Myxococcus xanthus are defective in production of extracellular A-signal, which serves as a cell density signal for fruiting-body development. The DNA sequence of asgB, one of the three asg genes, was determined. The deduced amino acid sequence of AsgB contains a DNA-binding helix-turn-helix motif near the C terminus. This putative helix-turn-helix is highly similar to the helix-turn-helix in region 4.2 of major sigma factors, which is the region that recognizes and interacts with -35 sequences of promoters. We propose that AsgB is a transcription factor that binds to DNA sequences similar to the -35 hexamer, TTGACA. Analyses of asgB RNA levels and expression of an asgB-lacZ translational fusion indicate that expression of asgB remains fairly constant during the transition from growth into early development. The mutation within the asgB480 allele was identified as an A-to-G transition that results in a threonine-to-alanine substitution in the predicted protein product. Attempts to replace the wild-type copy of asgB with a null allele failed, indicating that asgB may be essential for growth.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.