ArticleBMJ (Clinical research ed.)1994
Case-control study of intrapartum care, cerebral palsy, and perinatal death.
Article in BMJ (Clinical research ed.), 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Reducing stillbirths: interventions during labour.BMC pregnancy and childbirth · 2009Pooled it
- Computerised interpretation of fetal heart rate during labour (INFANT): a randomised controlled trial.Lancet (London, England) · 2017Trial
- A study of an intelligent system to support decision making in the management of labour using the cardiotocograph - the INFANT study protocol.BMC pregnancy and childbirth · 2016Trial
- Altered adult brain morphology in a mouse model of late-onset fetal growth restriction.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Correlation between fetal heart rate evolution patterns and magnetic resonance imaging findings in severe cerebral palsy: A longitudinal study.BJOG : an international journal of obstetrics and gynaecology · 2022Article
- A Retrospective Review of Decision to Delivery Time Interval for Foetal Distress at a Central Hospital.International journal of women's health · 2022Article
- Concordance analysis of intrapartum cardiotocography between physicians and artificial intelligence-based technique using modified one-dimensional fully convolutional networks.Journal of the Chinese Medical Association : JCMA · 2021Article
- The impact of high intensity care around birth on long-term neurodevelopmental outcomes.Health economics review · 2020Article
- Prelabor rupture of membranes and the association with cerebral palsy in term born children: a national registry-based cohort study.BMC pregnancy and childbirth · 2020Article
- S1-Guideline on the Use of CTG During Pregnancy and Labor: Long version - AWMF Registry No. 015/036.Geburtshilfe und Frauenheilkunde · 2014Article
- Mediators of the association between pre-eclampsia and cerebral palsy: population based cohort study.BMJ (Clinical research ed.) · 2013Article
- Electronic Fetal Monitoring: A Defense Lawyer's View.Reviews in obstetrics & gynecology · 2012Article
- Low Apgar score and mortality in extremely preterm neonates born in the United States.Acta paediatrica (Oslo, Norway : 1992) · 2010Article
- Monocarboxylate transporter 8 expression in the human placenta: the effects of severe intrauterine growth restriction.The Journal of endocrinology · 2006Article
- Maternal nutrient deprivation induces sex-specific changes in thyroid hormone receptor and deiodinase expression in the fetal guinea pig brain.The Journal of physiology · 2005Article
- Why is there a modifying effect of gestational age on risk factors for cerebral palsy?Archives of disease in childhood. Fetal and neonatal edition · 2005Article
- Article
- The Scottish perinatal neuropathology study: clinicopathological correlation in early neonatal deaths.Archives of disease in childhood. Fetal and neonatal edition · 2004Article
- Postmaturity in a genetic subtype of schizophrenia.Acta psychiatrica Scandinavica · 2003Article
- Caesarean section for fetal distress.BMJ (Clinical research ed.) · 2001Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the relation between suboptimal intrapartum obstetric care and cerebral palsy or death.
designCase-control study.
settingOxford Regional Health Authority. SUBJECTS: 141 babies who subsequently developed cerebral palsy and 62 who died intrapartum or neonatally, 1984-7. All subjects were born at term of singleton pregnancies and had no congenital anomaly. Two controls, matched for place and time of birth, were selected for each index case.
main outcome measuresAdverse antenatal factors and suboptimal intrapartum care (by using predefined criteria).
resultsFailure to respond to signs of severe fetal distress was more common in cases of cerebral palsy (odds ratio 4.5; 95% confidence interval 2.4 to 8.4) and in cases of death (26.1; 6.2 to 109.7) than among controls. This association persisted even after adjustment for increased incidence of a complicated obstetric history in cases of cerebral palsy. Neonatal encephalopathy is regarded as the best clinical indicator of birth asphyxia; only two thirds (23/33) of the children with cerebral palsy in whom there had been a suboptimal response to fetal distress, however, had evidence of neonatal encephalopathy; these 23 formed 6.8% of all children with cerebral palsy born to residents of the region in the four years studied.
conclusionThere is an association between quality of intrapartum care and death. The findings also suggest an association between suboptimal care and cerebral palsy, but this seems to have a role in only a small proportion of all cases of cerebral palsy. The contribution of adverse antenatal factors in the origin of cerebral palsy needs further study.
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