Evidence map›Paper›PMID 8139052›Full record

ArticleJournal of virology1994

Transformation of myelomonocytic cells by the avian myeloblastosis virus is determined by the v-myb oncogene, not by the unique long terminal repeats of the virus.

U Engelke, J S Lipsick

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Transformation by v-Myb.Oncogene · 1999
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

U EngelkeDepartment of Pathology, Stanford University School of Medicine, California 94305-5324.
J S Lipsick
Stanford University · US

Funding

MECHANISM OF TRANSFORMATION BY THE V-MYB ONCOGENESR01CA043592 · NCI · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI LIPSICK, JOSEPH STEVEN · 1987 to 2005
$1.5M
TRANSFORMATION BY THE MYB ONCOGENEK04CA001457 · NCI · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI LIPSICK, JOSEPH STEVEN · 1989 to 1993
–
NCI NIH HHS KO4 CA01457NCI NIH HHS R01 CA43592
6 · The paper itself

Abstract

The avian myeloblastosis virus (AMV) induces acute monoblastic leukemia in chickens and transforms only myelomonocytic cells in vitro. The long terminal repeat (LTR) regulatory region of AMV is unique among the known classes of avian retrovirus LTRs. We demonstrate that the substitution of the AMV LTRs by Rous sarcoma virus LTRs did not alter the cell type specificity or the transforming ability of the virus.

Indexed as

OncogenesAnimalsAvian Myeloblastosis VirusBase SequenceCell Transformation, ViralChick EmbryoGenome, ViralHelper VirusesHematopoietic Stem CellsMolecular Sequence DataProvirusesRepetitive Sequences, Nucleic Acid

Identifiers

PMID8139052
PMCPMC236755
OpenAlexW1524867855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.