ArticleJournal of muscle research and cell motility1993
The binding of fluorescent phallotoxins to actin in myofibrils.
Article in Journal of muscle research and cell motility, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- ETS1, a Target Gene of the EWSR1::FLI1 Fusion Oncoprotein, Regulates the Expression of the Focal Adhesion Protein TENSIN3.Molecular cancer research : MCR · 2024Article
- Affimer proteins for F-actin: novel affinity reagents that label F-actin in live and fixed cells.Scientific reports · 2018Article
- A Novel Method of Determining the Functional Effects of a Minor Genetic Modification of a Protein.Frontiers in cardiovascular medicine · 2015Article
- Cross-bridge kinetics in myofibrils containing familial hypertrophic cardiomyopathy R58Q mutation in the regulatory light chain of myosin.Journal of theoretical biology · 2011Article
- Myosin cross-bridges do not form precise rigor bonds in hypertrophic heart muscle carrying troponin T mutations.Journal of molecular and cellular cardiology · 2011Article
- Familial hypertrophic cardiomyopathy can be characterized by a specific pattern of orientation fluctuations of actin molecules .Biochemistry · 2010Article
- Observing cycling of a few cross-bridges during isometric contraction of skeletal muscle.Cytoskeleton (Hoboken, N.J.) · 2010Article
- Single molecule kinetics in the familial hypertrophic cardiomyopathy D166V mutant mouse heart.Journal of molecular and cellular cardiology · 2010Article
- Fluorescence lifetime of actin in the familial hypertrophic cardiomyopathy transgenic heart.Biochemistry · 2009Article
- Nebulin interacts with CapZ and regulates thin filament architecture within the Z-disc.Molecular biology of the cell · 2008Article
- Muscle anatomy is a primary determinant of muscle relaxation dynamics in the lobster (Panulirus interruptus) stomatogastric system.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2007Article
- Decreasing photobleaching by silver island films: application to muscle.Analytical biochemistry · 2007Article
- Changes in orientation of actin during contraction of muscle.Biophysical journal · 2004Article
- Simultaneous measurement of rotations of myosin, actin and ADP in a contracting skeletal muscle fiber.Journal of muscle research and cell motility · 2004Article
- Distribution of sarcomere length and intracellular calcium in mouse skeletal muscle following stretch-induced injury.The Journal of physiology · 1997Article
- A study on the mechanism of phalloidin-induced tension changes in skinned rabbit psoas muscle fibres.Journal of muscle research and cell motility · 1996Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Fluorescence microscope observation of myofibrils incubated with rhodamine-phalloidin and coumarine-phallacidin showed an initial appearance of fluorescence bands at the Z-lines and near the middle of the sarcomeres indicating preferential binding of dye to actin subunits located at both actin filament ends. After long incubation times (1-3 h) however, a final pattern is reached which consists of fluorescent Z-lines in the center of uniformly labelled actin bands, with greater fluorescence in the Z-lines than in the uniform region outside the Z-lines. Increasing the temperature or the ionic strength increased the rate of change to the final pattern. These data indicate: (1) that the ends of the actin filament are kinetically more accessible to phallotoxins; (2) at long times when equilibrium binding presumably occurs, the concentration of actin subunits in the Z-band is greater than in the rest of the sarcomere.
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Registered trials
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