ArticleThe Journal of physiology1993
Calcium channel currents recorded from isolated myocytes of rat basilar artery are stretch sensitive.
Article in The Journal of physiology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 129 citations in OpenAlex.
- Meta-Analysis of Mechano-Sensitive Ion Channels in Human Hearts: Chamber- and Disease-Preferential mRNA Expression.International journal of molecular sciences · 2023Pooled it
- Rhythmic calcium transients in smooth muscle cells of the mouse internal anal sphincter.Neurogastroenterology and motility · 2020Article
- Regulation of Membrane Calcium Transport Proteins by the Surrounding Lipid Environment.Biomolecules · 2019Review
- Mechanosensitive Piezo Channels in the Gastrointestinal Tract.Current topics in membranes · 2017Review
- Mechanosensitive gating of Kv channels.PloS one · 2015Review
- Distinct roles of L- and T-type voltage-dependent Ca2+ channels in regulation of lymphatic vessel contractile activity.The Journal of physiology · 2014Article
- The role of mechanotransduction on vascular smooth muscle myocytes' [corrected] cytoskeleton and contractile function.Anatomical record (Hoboken, N.J. : 2007) · 2014Review
- Mechanical regulation of native and the recombinant calcium channel.Cell calcium · 2013Article
- Regulation of vascular smooth muscle mechanotransduction by microRNAs and L-type calcium channels.Communicative & integrative biology · 2013Article
- Article
- Electrolyte therapy reduces spike-and-wave discharges in the WAG/Rij rat model of absence epilepsy.Epilepsy & behavior : E&B · 2012Article
- Mechanical control of cation channels in the myogenic response.American journal of physiology. Heart and circulatory physiology · 2011Article
- Spatial association of the Cav1.2 calcium channel with α5β1-integrin.American journal of physiology. Cell physiology · 2011Article
- Stimulated calcium entry and constitutive RhoA kinase activity cause stretch-induced detrusor contraction.European journal of pharmacology · 2008Article
- Membrane stretch slows the concerted step prior to opening in a Kv channel.The Journal of general physiology · 2006Article
- Membrane tension accelerates rate-limiting voltage-dependent activation and slow inactivation steps in a Shaker channel.The Journal of general physiology · 2004Article
- 20-Hydroxyeicosatetraenoic acid potentiates stretch-induced contraction of canine basilar artery via PKC alpha-mediated inhibition of KCa channel.British journal of pharmacology · 2002Article
- Mechanosensitivity of N-type calcium channel currents.Biophysical journal · 2002Article
- Membrane stretch accelerates activation and slow inactivation in Shaker channels with S3-S4 linker deletions.Biophysical journal · 2002Article
- Cytochalasin D reduces Ca2+ currents via cofilin-activated depolymerization of F-actin in guinea-pig cardiomyocytes.The Journal of physiology · 2001Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
1. Conventional and perforated patch whole-cell methods were used to measure Ca2+ channel currents from isolated rat basilar arterial myocytes in response to voltage steps. Peak currents measured in response to repeated steps to +2 mV increased over the first 3 min after gaining whole-cell access. The increase followed an exponential time course, was not due to decrease in underlying outward current and was independent of the presence of ATP and GTP in the pipette filling solution. 2. Application of positive and negative pressure to the pipette resulted in significant increase and decrease in peak inward current, respectively. Membrane stretch, associated with changes in cell volume, rather than applied pressure per se appeared to determine changes in peak current. 3. Using amphotericin B perforated patch recording, changes in cell volume on application of 80% hypo- or 120% hyperosmotic superfusing solutions were found to effect similarly peak inward current. Hyposmotically induced cell swelling increased and hyperosmotic cell shrinkage decreased peak inward current at all test potentials studied. 4. The increase in inward current in response to hyposmotic superfusate was reversible and appears to reflect an increase in voltage-dependent Ca2+ channel current since it was not due to a change in non-voltage-sensitive conductance(s) and it was as sensitive as the control current to the dihydropyridine (DHP) antagonist (-)202-791.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.