Evidence map›Paper›PMID 8119731›Full record

ArticleImmunogenetics1994

Association of four antigens of the tetraspans family (CD37, CD53, TAPA-1, and R2/C33) with MHC class II glycoproteins.

P Angelisová, I Hilgert, V Horejsí

Abstract read
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In one paragraph

Article in Immunogenetics, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 175 citations in OpenAlex.

  1. Article
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  4. Tetraspanin-5-mediated MHC class I clustering is required for optimal CD8 T cell activation.Proceedings of the National Academy of Sciences of the United States of America · 2022
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  8. Membrane Compartmentalization and Scaffold Proteins in Leukocyte Migration.Frontiers in cell and developmental biology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

P AngelisováInstitute of Molecular Genetics, Academy of Sciences of the Czech Republic, Praha.
I Hilgert
V Horejsí
Czech Academy of Sciences · CZCzech Academy of Sciences, Institute of Molecular Genetics · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four of the tetraspans family antigens expressed in B cells, CD37, CD53, TAPA-1, and R2/C33, as well as at least two other molecules, CD19 and CD21, coprecipitate with DR antigens from mild detergent lysates of human B-cell lines and tonsillar B cells. Coprecipitation and preclearing experiments indicate the existence of large multicomponent complexes containing jointly the seven components, although some "incomplete" complexes lacking some of the components may also exist. The complexes contain only a relatively small fraction of the total cellular pool of relevant molecules. The existence of these "tetraspans-DR complexes" may be related to the previously reported antiproliferative and signaling effects of antibodies against most of their components.

Indexed as

Antigens, NeoplasmMembrane GlycoproteinsMembrane ProteinsProto-Oncogene ProteinsAntibodies, MonoclonalAntigens, CDAntigens, DifferentiationAntigens, Differentiation, T-LymphocyteAntigens, SurfaceBlotting, WesternB-LymphocytesCell LineGlycoproteinsHLA-DR AntigensHumansKangai-1 ProteinAntibodies, MonoclonalAntigens, CDAntigens, DifferentiationAntigens, Differentiation, T-LymphocyteAntigens, NeoplasmAntigens, SurfaceCD37 protein, humanCD53 protein, humanCD81 protein, humanCD82 protein, humanGlycoproteinsHLA-DR AntigensKangai-1 ProteinMembrane GlycoproteinsMembrane ProteinsProto-Oncogene ProteinsTetraspanin 25Tetraspanin 28Tetraspanins

Identifiers

PMID8119731
OpenAlexW2014115532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.