ReviewEuropean archives of psychiatry and clinical neuroscience1993
Identification of the phenotype in psychiatric genetics.
Review in European archives of psychiatry and clinical neuroscience, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00071786 (Family Study of Affective and Anxiety Spectrum Disorders), which is not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Family Study of Affective and Anxiety Spectrum Disorders
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Neurological soft signs are not "soft" in brain structure and functional networks: evidence from ALE meta-analysis.Schizophrenia bulletin · 2014Pooled it
- Imaging genetic liability to schizophrenia: systematic review of FMRI studies of patients' nonpsychotic relatives.Schizophrenia bulletin · 2009Pooled it
- Ordered subset linkage analysis based on admixture proportion identifies new linkage evidence for alcohol dependence in African-Americans.Human genetics · 2013Trial
- An "Eight Perspectives" framework to describe complex psychobehavioral phenomena.Frontiers in psychology · 2026Article
- Using Alternative Definitions of Controls to Increase Statistical Power in GWAS.Behavior genetics · 2024Article
- Genetic influences on alcohol sensitivity: A critical review.Current addiction reports · 2024Article
- Evaluating endophenotypes for bipolar disorder.International journal of bipolar disorders · 2021Review
- Fluid Reasoning Mediates the Association of Birth Weight With ADHD Symptoms in Youth From Multiplex Families With ADHD.Journal of attention disorders · 2019Article
- Psychiatric genetics and the structure of psychopathology.Molecular psychiatry · 2019Review
- Recent Genetics and Epigenetics Approaches to PTSD.Current psychiatry reports · 2018Review
- Decreased white matter FA values in the left inferior frontal gyrus is a possible intermediate phenotype of schizophrenia: evidences from a novel group strategy.European archives of psychiatry and clinical neuroscience · 2018Article
- Cross-generational influences on childhood anxiety disorders: pathways and mechanisms.Journal of neural transmission (Vienna, Austria : 1996) · 2016Review
- Multidimensional assessment of impulsivity in schizophrenia, bipolar disorder, and major depressive disorder: testing for shared endophenotypes.Psychological medicine · 2016Article
- Coping Styles in Twins Discordant for Schizophrenia, Bipolar Disorder, and Depression.Clinical psychological science : a journal of the Association for Psychological Science · 2016Article
- EEG-Informed fMRI Reveals a Disturbed Gamma-Band-Specific Network in Subjects at High Risk for Psychosis.Schizophrenia bulletin · 2016Article
- Genetics in child and adolescent psychiatry: methodological advances and conceptual issues.European child & adolescent psychiatry · 2015Review
- Prenatal maternal immune disruption and sex-dependent risk for psychoses.Psychological medicine · 2014Article
- Evidence for disturbed insulin and growth hormone signaling as potential risk factors in the development of schizophrenia.Translational psychiatry · 2014Article
- Correction of phenotype misclassification based on high-discrimination genetic predictive risk models.Epidemiology (Cambridge, Mass.) · 2012Article
- Neuroeconomics: a bridge for translational research.Biological psychiatry · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Statistical procedures and molecular genetic techniques have attained a fine degree of resolution. Their ability to find disease genes has revolutionized medicine and raised hopes for breakthroughs in psychiatry. However, such breakthroughs may require an equally discriminating nosology. A psychiatric genetic nosology seeks to classify patients into categories that correspond to distinct genetic entities by addressing the problem of diagnostic accuracy: the degree to which a diagnosis correctly classifies people with and without a putative genetic illness. We review methods that deal with misclassification in genetic studies. These are clinical and epidemiological approaches that deal directly with how to define the observable manifestation of a putative genotype. We discuss two groups of methods: those that use known phenotypes and those that design new phenotypes.
Indexed as
Identifiers
8117756What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.