ArticleAmerican journal of human genetics1994
Genetic mapping of the BRCA1 region on chromosome 17q21.
Article in American journal of human genetics, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Breast cancer incidence and subtype patterns among BRCA-mutated ovarian cancer patients: a systematic review and meta-analysis.British journal of cancer · 2026Pooled it
- Canadian Recommendations for Germline Genetic Testing of Patients with Breast Cancer: A Call to Action.Current oncology (Toronto, Ont.) · 2025Article
- BRCA genetic testing and counseling in breast cancer: how do we meet our patients' needs?NPJ breast cancer · 2024Review
- Developments in Genetics: Better Management of Ovarian Cancer Patients.International journal of molecular sciences · 2023Review
- Mitochondrial Disruption by Amyloid Beta 42 Identified by Proteomics and Pathway Mapping.Cells · 2021Article
- Review
- New Perspectives for Resistance to PARP Inhibitors in Triple-Negative Breast Cancer.Frontiers in oncology · 2020Review
- A salpingeal carcinoma revealed after prophylactic salpingoophorectomy in an asymptomatic BRCA1 carrier with breast malignancy.International journal of surgery case reports · 2018Article
- BRCA1 and BRCA2 mutations and treatment strategies for breast cancer.Integrative cancer science and therapeutics · 2017Article
- A Retrospective Exploration of the Impact of the 'Angelina Jolie Effect' on the Single State-Wide Familial Cancer Program in Perth, Western Australia.Journal of genetic counseling · 2017Article
- The European BRCA patent oppositions and appeals: coloring inside the lines.Nature biotechnology · 2013Article
- An analysis of the feasibility of short read sequencing.Nucleic acids research · 2005Article
- Functional evidence for the presence of tumor suppressor gene on chromosome 10p15 in human prostate cancers.Oncogene · 2001Article
- The 1999 Reginald Thomson Lecture. Custom-built mice: unique discovery tools in biomedical research.The Canadian veterinary journal = La revue veterinaire canadienne · 2000Article
- Identification of genetic changes associated with drug resistance by reverse in situ hybridization.British journal of cancer · 1997Article
- A collection of ordered tetranucleotide-repeat markers from the human genome. The Utah Marker Development Group.American journal of human genetics · 1995Article
- A radiation hybrid map of the BRCA1 region.American journal of human genetics · 1994Article
- Screening, diagnosis and genetic study of breast cancer patients in Pakistan.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
Chromosome 17q21 harbors a gene (BRCA1) associated with a hereditary form of breast cancer. As a step toward identification of this gene itself we developed a number of simple-sequence-repeat (SSR) markers for chromosome 17 and constructed a high-resolution genetic map of a 40-cM region around 17q21. As part of this effort we captured genotypes from five of the markers by using an ABI sequencing instrument and stored them in a locally developed database, as a step toward automated genotyping. In addition, YACs that physically link some of the SSR markers were identified. The results provided by this study should facilitate physical mapping of the BRCA1 region and isolation of the BRCA1 gene.
Indexed as
Identifiers
8116621PMC1918118W88789081What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.