Evidence map›Paper›PMID 8112695›Full record

ArticleFolia microbiologica1993

Host response to Mycobacterial cell wall subunit during experimental tuberculosis in mice.

I B Chugh, V K Vinayak, G K Khuller

Abstract read
PubMed Publisher
In one paragraph

Article in Folia microbiologica, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

I B ChughDepartment of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
V K Vinayak
G K Khuller
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cell-wall protein-peptidoglycan complex (CW-PPC) of Mycobacterium tuberculosis, an immunologically potent component, was used to study the correlation between immune response and in vivo bacterial multiplication in the course of experimental tuberculosis infection in mice. Antibodies to CW-PPC were detected only after seven weeks of infection with M. tuberculosis H37Rv and afterwards no significant change was seen throughout the experiment. Delayed type hypersensitivity (DTH) to CW-PPC showed a gradual increase from the fifth week onward with a maximum during the 12th week after infection (p.in.) which did not change significantly afterward. The increased immune response in the course of infection correlated well with the multiplication rate of bacilli in the lungs. These results indicate a role of CW-PPC in antituberculous immunity.

Indexed as

AnimalsAntibodies, BacterialCell WallFemaleHypersensitivity, DelayedLungMaleMiceMycobacterium tuberculosisTuberculosisAntibodies, Bacterial

Identifiers

PMID8112695
OpenAlexW2015731504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.