ArticleProceedings of the National Academy of Sciences of the United States of America1994
A developmentally regulated basic-leucine zipper-like gene and its expression in embryonic retina and lens.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 37 citations in OpenAlex.
- Reprogramming retinal pigment epithelium to differentiate toward retinal neurons with Sox2.Stem cells (Dayton, Ohio) · 2009Article
- A role of ath5 in inducing neuroD and the photoreceptor pathway.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004Article
- Cloning and characterization of a novel transcription factor involved in cellular proliferation arrest: PATF.Oncogene · 2001Article
- Misexpression of a bHLH gene, cNSCL1, results in abnormal brain development.Developmental dynamics : an official publication of the American Association of Anatomists · 1999Article
- neuroD induces photoreceptor cell overproduction in vivo and de novo generation in vitro.Journal of neurobiology · 1998Article
- A hydrophobic heptad repeat of the core protein of woodchuck hepatitis virus is required for capsid assembly.Journal of virology · 1996Article
- The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Chromokinesin: a DNA-binding, kinesin-like nuclear protein.The Journal of cell biology · 1995Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Transcriptional regulators play important roles in the control of key developmental events. We have identified sw3-3, a likely candidate for such a function, in tissues of the eye and other neural organs. It encodes a basic-leucine zipper-like protein, in which two leucine zipper motifs flank a basic domain. The latter contains helix-disturbing amino acids such as glycine and proline, at positions occupied by conserved asparagine and alanine residues (respectively) in "conventional" basic-leucine zipper proteins. sw3-3 is widely expressed at early embryonic stages in the lens, retina, and other neural tissues and is down-regulated thereafter with a spatial and temporal pattern that correlates with the cessation of mitotic activity and the onset of cell migration and differentiation.
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Registered trials
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