ReviewProceedings of the National Academy of Sciences of the United States of America1993
Alzheimer disease and the prion disorders amyloid beta-protein and prion protein amyloidoses.
Review in Proceedings of the National Academy of Sciences of the United States of America, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- The Systemic Effects of Exercise on the Systemic Effects of Alzheimer's Disease.Antioxidants (Basel, Switzerland) · 2022Review
- Evidence of a Prion-Like Transmission of p53 Amyloid in Saccharomyces cerevisiae.Molecular and cellular biology · 2017Article
- At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei.Neuropathology and applied neurobiology · 2015Article
- Amyloid fibril formation in vitro from halophilic metal binding protein: its high solubility and reversibility minimized formation of amorphous protein aggregations.Protein science : a publication of the Protein Society · 2013Article
- Review: microglia of the aged brain: primed to be activated and resistant to regulation.Neuropathology and applied neurobiology · 2013Review
- Article
- Genetic cross-interaction between APOE and PRNP in sporadic Alzheimer's and Creutzfeldt-Jakob diseases.PloS one · 2011Article
- Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005Article
- Comparison of inflammatory and acute-phase responses in the brain and peripheral organs of the ME7 model of prion disease.Journal of virology · 2005Article
- Genetic studies in Alzheimer's disease.Dialogues in clinical neuroscience · 2003Article
- Cellular biology of prion diseases.Clinical microbiology reviews · 1999Review
- Lipid thioesters derived from acylated proteins accumulate in infantile neuronal ceroid lipofuscinosis: correction of the defect in lymphoblasts by recombinant palmitoyl-protein thioesterase.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Theiler's virus as a vector for foreign gene delivery.Journal of virology · 1995Article
- Transmembrane kit ligand cleavage does not require a signal in the cytoplasmic domain and occurs at a site dependent on spacing from the membrane.Molecular biology of the cell · 1994Article
- Transthyretin sequesters amyloid beta protein and prevents amyloid formation.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Ribozyme mediated degradation of beta-amyloid peptide precursor mRNA in COS-7 cells.Nucleic acids research · 1994Article
- Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
Alzheimer disease and the prion disorders/spongiform encephalopathies share many common features. These chronic, progressive, sometimes familial diseases of the central nervous system are characterized by the presence of different types of amyloid deposits in the brain. This review provides a perspective on these two types of neurodegenerative disorders.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.