Evidence map›Paper›PMID 8096640›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1993

Homeobox genes are expressed in the retina and brain of adult goldfish.

E M Levine, N Schechter

Open access · greenAbstract readComparative Study
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Conservation of the TGFbeta/Labial homeobox signaling loop in endoderm-derived cells between Drosophila and mammals.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2010
    Article
  3. Article
  4. The duplication of the Hox gene clusters in teleost fishes.Theory in biosciences = Theorie in den Biowissenschaften · 2004
    Article
  5. Article
  6. Expression of pax-6 during urodele eye development and lens regeneration.Proceedings of the National Academy of Sciences of the United States of America · 1995
    Article
  7. Article
  8. A developmentally regulated basic-leucine zipper-like gene and its expression in embryonic retina and lens.Proceedings of the National Academy of Sciences of the United States of America · 1994
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

E M LevineDepartment of Biochemistry and Cell Biology, State University of New York, Stony Brook 11794.
N Schechter
Stony Brook University · US

Funding

NEI NIH HHS EY 05212
6 · The paper itself

Abstract

The goldfish (Carassius auratus) visual pathway displays continuous growth and plasticity throughout life. Since homeobox genes are important transcriptional regulators in development, we searched for homeobox genes in the adult goldfish retina and brain. Using the PCR, we discovered a repertoire of homeobox sequences expressed in these tissues. In addition to isolating homeodomain sequences found in the vertebrate Hox gene clusters, a sequence identical to the chicken CHox7 homeodomain was characterized. Furthermore, a sequence with significant homologies to the Xenopus XIHbox8 and leech Htr-A2 homeodomains was identified, and these sequences may define an additional class of homeodomain. Finally, a sequence belonging to the paired class (prd) of homeodomains is reported. Homeobox gene expression in the adult goldfish retina and brain may be associated with the persistent developmental features of these tissues.

Indexed as

Genes, HomeoboxMultigene FamilyAmino Acid SequenceAnimalsBase SequenceBrainChickensCloning, MolecularDNAGoldfishHumansLeechesMolecular Sequence DataPolymerase Chain ReactionRetinaSequence Homology, Amino AcidDNA

Identifiers

PMID8096640
PMCPMC46169
OpenAlexW1973890187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.