ArticleHuman genetics1993
Three Finnish incontinentia pigmenti (IP) families with recombinations with the IP loci at Xq28 and Xp11.
Article in Human genetics, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 13 citations in OpenAlex.
- De novo mutation in three families with multigenerational incontinentia pigmenti.American journal of human genetics · 1994Article
- Incontinentia pigmenti nomenclature.American journal of human genetics · 1994Review
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3 authors at 1 institution in 1 country.
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Abstract
The locus (IP2) for the hereditary form of incontinentia pigmenti (IP) has been mapped to Xq28 by linkage analysis. We studied three IP families with polymorphic markers in the Xq28 region. In two families we observed recombination between the marker loci and IP. In the third family no crossing overs were seen and linkage to the Xq28 region could not be excluded. The other IP locus (IP1) has been mapped to Xp11.21, because of sporadic cases of IP with X-chromosomal alterations involving Xp11.21. To check whether this locus is linked to IP in these families, we used polymorphic markers in the Xp11 region. In all three families recombinations were observed, thus excluding linkage to this locus in these IP families.
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