ArticleJournal of clinical pathology1994
Human papillomavirus detection by hybrid capture and its possible clinical use.
Article in Journal of clinical pathology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Human papillomavirus typing in HIV-positive women.Infectious diseases in obstetrics and gynecology · 2001Trial
- Hybrid capture II, a new sensitive test for human papillomavirus detection. Comparison with hybrid capture I and PCR results in cervical lesions.Journal of clinical pathology · 1998Trial
- Comparative analysis of human papillomavirus detection by PCR and non-isotopic in situ hybridisation.Journal of clinical pathology · 1995Trial
- Human papillomavirus type 16 viral load measurement as a predictor of infection clearance.The Journal of general virology · 2013Article
- Does pretreatment HPV viral load correlate with prognosis in patients with early stage cervical carcinoma?Journal of gynecologic oncology · 2008Article
- Polymerase chain reaction-based fluorescent Luminex assay to detect the presence of human papillomavirus types.Cancer science · 2007Article
- A quantitative polymerase chain reaction-enzyme immunoassay for accurate measurements of human papillomavirus type 16 DNA levels in cervical scrapings.British journal of cancer · 1999Article
- Hybrid Capture II-based human papillomavirus detection, a sensitive test to detect in routine high-grade cervical lesions: a preliminary study on 1518 women.British journal of cancer · 1999Article
- Comparative evaluation of first- and second-generation digene hybrid capture assays for detection of human papillomaviruses associated with high or intermediate risk for cervical cancer.Journal of clinical microbiology · 1999Article
- Human papillomavirus infection with particular reference to genital disease.Journal of clinical pathology · 1998Review
- Human papillomaviruses and cervical neoplasia. I. Classification, virology, pathology, and epidemiology.Journal of clinical pathology · 1994Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo determine the sensitivity of the hybrid capture method for human papillomavirus (HPV) detection and potential clinical uses as a screening method for the identification of cervical intraepithelial neoplasia.
methodsThe presence of oncogenic types of HPV was tested for in samples taken from the cervix at colposcopy, and compared with detection by polymerase chain reaction (PCR) in 60 patients. Both sets of results were corrected with the pathology determined by biopsy and smear cytology.
resultsHybrid capture detection showed 86% agreement with PCR. Eighty three percent of CIN 3 lesions, 62% of CIN 2, 59% of CIN 1 and 21% of normal controls were positive for oncogenic HPV types.
conclusionThe hybrid capture detection method is reliable, sensitive, and easy to use. The addition of HPV testing to cytological screening would detect a greater proportion of cervical dysplasia with a higher false positive rate.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.