ArticleAmerican journal of human genetics1994
Multipoint mapping calculations for sperm-typing data.
Article in American journal of human genetics, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 30 citations in OpenAlex.
- Constructing the parental linkage phase and the genetic map over distances <1 cM using pooled haploid DNA.Genetics · 2006Article
- High-resolution patterns of meiotic recombination across the human major histocompatibility complex.American journal of human genetics · 2002Article
- Absence of age effect on meiotic recombination between human X and Y chromosomes.American journal of human genetics · 2002Article
- Evidence for heterogeneity in recombination in the human pseudoautosomal region: high resolution analysis by sperm typing and radiation-hybrid mapping.American journal of human genetics · 2000Article
- SPERMSEG: analysis of segregation distortion in single-sperm data.American journal of human genetics · 1999Article
- Genetic analysis of meiotic recombination in humans by use of sperm typing: reduced recombination within a heterozygous paracentric inversion of chromosome 9q32-q34.3.American journal of human genetics · 1998Article
- Individual variation in recombination among human males.American journal of human genetics · 1996Article
- Analysis of meiotic segregation, using single-sperm typing: meiotic drive at the myotonic dystrophy locus.American journal of human genetics · 1996Article
- The behavior of meiosis in sperm.American journal of human genetics · 1994Article
- Multipoint linkage map of the human pseudoautosomal region, based on single-sperm typing: do double crossovers occur during male meiosis?American journal of human genetics · 1994Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper explains how multipoint likelihoods can be computed for sperm-typing data. Experimental errors such as multiple sperm per tube, inadequate amplification, and contamination by exogenous DNA are explicitly taken into account. By limiting the number of sperm theoretically possible per tube to a predetermined maximum and by assuming no chiasma interference, maximum-likelihood estimation can be carried out rapidly using the theory of hidden Markov chains.
Indexed as
Identifiers
8079987PMC1918392W1492369005What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.