ArticleAmerican journal of human genetics1994
Multipoint linkage map of the human pseudoautosomal region, based on single-sperm typing: do double crossovers occur during male meiosis?
Article in American journal of human genetics, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 50 citations in OpenAlex.
- Where is the boundary of the human pseudoautosomal region?American journal of human genetics · 2024Article
- Genetic architecture of individual variation in recombination rate on the X chromosome in cattle.Heredity · 2020Article
- Detection of SHOX gene aberrations in routine diagnostic practice and evaluation of phenotype scoring form effectiveness.Journal of human genetics · 2017Article
- Recombination in the human Pseudoautosomal region PAR1.PLoS genetics · 2014Article
- Expansion of the pseudo-autosomal region and ongoing recombination suppression in the Silene latifolia sex chromosomes.Genetics · 2013Article
- A first-generation microsatellite-based genetic linkage map of the Siberian jay (Perisoreus infaustus): insights into avian genome evolution.BMC genomics · 2009Article
- Hot and cold spots of recombination in the human genome: the reason we should find them and how this can be achieved.American journal of human genetics · 2003Review
- High-resolution patterns of meiotic recombination across the human major histocompatibility complex.American journal of human genetics · 2002Article
- Absence of age effect on meiotic recombination between human X and Y chromosomes.American journal of human genetics · 2002Article
- Comprehensive human genome amplification using multiple displacement amplification.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Characterization of human crossover interference.American journal of human genetics · 2000Article
- Evidence for heterogeneity in recombination in the human pseudoautosomal region: high resolution analysis by sperm typing and radiation-hybrid mapping.American journal of human genetics · 2000Article
- Genetic analysis of meiotic recombination in humans by use of sperm typing: reduced recombination within a heterozygous paracentric inversion of chromosome 9q32-q34.3.American journal of human genetics · 1998Article
- Skewed segregation of the mtDNA nt 8993 (T-->G) mutation in human oocytes.American journal of human genetics · 1997Article
- An integrated genetic and physical map of the bovine X chromosome.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- Individual variation in recombination among human males.American journal of human genetics · 1996Article
- Analysis of meiotic segregation, using single-sperm typing: meiotic drive at the myotonic dystrophy locus.American journal of human genetics · 1996Article
- Mechanisms underlying telomere repeat turnover, revealed by hypervariable variant repeat distribution patterns in the human Xp/Yp telomere.The EMBO journal · 1995Article
- Interval mapping of high growth (hg), a major locus that increases weight gain in mice.Genetics · 1995Article
- Multipoint mapping calculations for sperm-typing data.American journal of human genetics · 1994Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sperm typing was used to measure recombination fractions among pseudoautosomal markers and the beginning of the X/Y-specific sequences located at the pseudoautosomal boundary. These experiments included primer-extension preamplification and PCR followed by allele typing using gel electrophoresis. A newly developed data-analysis program allowed the construction of the first multipoint-linkage sperm-typing map, using results obtained on seven loci from three individuals. The large sample size not only confirmed the increased recombination activity of the pseudoautosomal region but allowed an estimate of interference of recombination to be made. The coefficient of coincidence was calculated to be .26 over a physical distance of only approximately 1,800 kb. The observation of a few sperm presumably resulting from double recombination argues that more than one crossover event can occur in this region during male meiosis.
Indexed as
Identifiers
8079986PMC1918414W1574179830What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.