ArticleMammalian genome : official journal of the International Mammalian Genome Society1994
Maps from two interspecific backcross DNA panels available as a community genetic mapping resource.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 182 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
182 citing papers in PubMed, 584 citations in OpenAlex.
- Meiotic drive in house mice: mechanisms, consequences, and insights for human biology.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2022Review
- Mouse Genome Informatics (MGI) Resource: Genetic, Genomic, and Biological Knowledgebase for the Laboratory Mouse.ILAR journal · 2017Review
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- Mouse Genome Informatics (MGI): reflecting on 25 years.Mammalian genome : official journal of the International Mammalian Genome Society · 2015Review
- A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.PLoS genetics · 2015Article
- Loss of maternal CTCF is associated with peri-implantation lethality of Ctcf null embryos.PloS one · 2012Article
- Genetic mapping and developmental timing of transmission ratio distortion in a mouse interspecific backcross.BMC genetics · 2010Article
- Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2010Article
- A new standard genetic map for the laboratory mouse.Genetics · 2009Article
- Genomic copy number and expression variation within the C57BL/6J inbred mouse strain.Genome research · 2008Article
- Patterns of recombination and MLH1 foci density along mouse chromosomes: modeling effects of interference and obligate chiasma.Genetics · 2007Article
- Disruption of ephrin signaling associates with disordered axophilic migration of the gonadotropin-releasing hormone neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005Article
- The Anp32 family of proteins containing leucine-rich repeats.Cerebellum (London, England) · 2005Review
- Normal embryonic and germ cell development in mice lacking alpha 1,3-fucosyltransferase IX (Fut9) which show disappearance of stage-specific embryonic antigen 1.Molecular and cellular biology · 2004Article
- Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus.Molecular and cellular biology · 2004Article
- The development of a highly informative mouse Simple Sequence Length Polymorphism (SSLP) marker set and construction of a mouse family tree using parsimony analysis.Genome research · 2003Article
- Mapping quantitative trait loci in the case of a spike in the phenotype distribution.Genetics · 2003Article
- The comprehensive mouse radiation hybrid map densely cross-referenced to the recombination map: a tool to support the sequence assemblies.Genome research · 2003Article
- Article
- The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse.Protein science : a publication of the Protein Society · 2002Article
122 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
We established two mouse interspecific backcross DNA panels, one containing 94 N2 animals from the cross (C57BL/6J x Mus spretus)F1 x C57BL/6J, and another from 94 N2 animals from the reciprocal backcross (C57BL/6J x SPRET/Ei)F1 x SPRET/Ei. We prepared large quantities of DNA from most tissues of each animal to create a community resource of interspecific backcross DNA for use by laboratories interested in mapping loci in the mouse. Initial characterization of the genetic maps of both panels has been completed. We used MIT SSLP markers, proviral loci, and several other sequence-defined genes to anchor our maps to other published maps. The BSB panel map (from the backcross to C57BL/6J) contains 215 loci and is anchored by 45 SSLP and 32 gene sequence loci. The BSS panel map (from the backcross to SPRET/Ei) contains 451 loci and is anchored by 49 SSLP loci, 43 proviral loci, and 60 gene sequence loci. To obtain a high density of markers, we used motif-primed PCR to "fingerprint" the panel DNAs. We constructed two maps, each representing one of the two panels. All new loci can be located with a high degree of certainty on the maps at current marker density. Segregation patterns in these data reveal several examples of transmission ratio distortion and permit analysis of the distribution of crossovers on individual chromosomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.