ArticleThe British journal of ophthalmology1994
Optic nerve head blood flow using a laser Doppler velocimeter and haemorheology in primary open angle glaucoma and normal pressure glaucoma.
Article in The British journal of ophthalmology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed, 145 citations in OpenAlex.
- Reproducibility and sensitivity of scanning laser Doppler flowmetry during graded changes in PO2.The British journal of ophthalmology · 1997Trial
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- APSified Peripapillary Vessel Density in Glaucoma Suspects and Open-Angle Glaucoma.Diagnostics (Basel, Switzerland) · 2026Article
- Association of Heart Rate Variability and Acceleration Plethysmography with Systemic Comorbidity Burden in Patients with Glaucoma.Biomedicines · 2025Article
- Assessment of Retinal Microcirculation in Primary Open-Angle Glaucoma Using Adaptive Optics and OCT Angiography: Correlation with Structural and Functional Damage.Journal of clinical medicine · 2025Article
- OCT Angiography of the Retina and the Choroid in the Macula in Patients with Normal Tension Glaucoma and Primary Open Angle Glaucoma.Diagnostics (Basel, Switzerland) · 2024Article
- Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank.Nature communications · 2023Article
- Intraocular Pressure-Lowering Effects of Trabeculectomy Versus MicroShunt Insertion in Rabbit Eyes.Translational vision science & technology · 2021Article
- Vascular Aspects in Glaucoma: From Pathogenesis to Therapeutic Approaches.International journal of molecular sciences · 2021Review
- Current Perspective of Hydrogen Sulfide as a Novel Gaseous Modulator of Oxidative Stress in Glaucoma.Antioxidants (Basel, Switzerland) · 2021Review
- Energy Metabolism in the Inner Retina in Health and Glaucoma.International journal of molecular sciences · 2021Review
- Autonomic Dysfunction and Blood Pressure in Glaucoma Patients: The Lifelines Cohort Study.Investigative ophthalmology & visual science · 2020Article
- Associations between changes in radial peripapillary capillaries and occurrence of disc hemorrhage in normal-tension glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Article
- Comparison of retinal microvascular changes in eyes with high-tension glaucoma or normal-tension glaucoma: a quantitative optic coherence tomography angiographic study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018Article
- Laser speckle flowgraphy derived characteristics of optic nerve head perfusion in normal tension glaucoma and healthy individuals: a Pilot study.Scientific reports · 2018Article
- Peripapillary Vessel Density Reversal after Trabeculectomy in Glaucoma.Journal of ophthalmology · 2018Article
- Vessel density in OCT angiography permits differentiation between normal and glaucomatous optic nerve heads.International journal of ophthalmology · 2018Article
- Peripapillary retinal vessel density in eyes with acute primary angle closure: an optical coherence tomography angiography study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2017Observational
- Quantitative optical coherence tomography angiography of macular vascular structure and foveal avascular zone in glaucoma.PloS one · 2017Article
- Optical Coherence Tomography Angiography Vessel Density in Healthy, Glaucoma Suspect, and Glaucoma Eyes.Investigative ophthalmology & visual science · 2016Observational
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optic disc blood flow velocity was measured in healthy patients, those with primary open angle glaucoma (POAG), and patients with normal pressure glaucoma (NPG). The velocity of the red blood cells (RBCs) in the capillaries of the optic nerve head (ONH) has been measured with a laser Doppler velocimeter (LDV), and blood viscosity has been evaluated notably by determining the aggregability of the RBCs with an erythroaggregameter. Our results in POAG patients and NPG patients showed that their optic nerve blood flow velocity was reduced and that the aggregability of the RBCs was increased. The hyperaggregability of the erythrocytes is responsible for the increase of the local viscosity in the papillary capillary network. These haemodynamic modifications observed in patients with glaucoma support the hypothesis of a vasogenic mechanism that could impair the optic nerve in glaucoma patients.
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