ArticleJournal of neurology, neurosurgery, and psychiatry1994
Peripheral neuropathy associated with primary Sjögren's syndrome.
Article in Journal of neurology, neurosurgery, and psychiatry, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 146 citations in OpenAlex.
- Recommendations on neurologic, cognitive, and psychiatric manifestations in patients with Sjögren's disease by the Brazilian Society of Rheumatology.Advances in rheumatology (London, England) · 2025Guideline
- Recommendations on cutaneous and hematological manifestations of Sjögren's disease by the Brazilian Society of Rheumatology.Advances in rheumatology (London, England) · 2024Guideline
- Primary Sjögren syndrome-related peripheral neuropathy: A systematic review and meta-analysis.European journal of neurology · 2023Pooled it
- Prevalence of Small A-Delta Fiber Neuropathy in Sjögren's Disease: Findings from a Cohort Study.International journal of molecular sciences · 2025Article
- Dysautonomia as a form of presentation of primary Sjögren's disease: a case series of six patients.Immunologic research · 2025Article
- Sjogren's syndrome: a neurological perspective.Arquivos de neuro-psiquiatria · 2023Review
- Peripheral nervous system involvement in Sjogren's syndrome and its impact on quality of life.Clinical and experimental medicine · 2023Observational
- Localized Cutaneous Nodular Amyloidosis: A Specific Cutaneous Manifestation of Sjögren's Syndrome.International journal of molecular sciences · 2023Review
- Analysis of clinical features and risk factors of peripheral neuropathy in patients with primary Sjögren's syndrome.European journal of medical research · 2023Article
- Granulocyte-colony-stimulating Factor-resistant Neutropenia and Polyneuropathy Presenting as Severe Complications of Sjögren's Syndrome.Internal medicine (Tokyo, Japan) · 2022Article
- Musculoskeletal Manifestations in Sjogren's Syndrome: An Orthopedic Point of View.Journal of clinical medicine · 2021Review
- COBRE for Skeletal Health and Repair: The Impact of Aging on the Capacity for Peripheral Nerve Regeneration.Rhode Island medical journal (2013) · 2021Review
- Ganglionic Acetylcholine Receptor Antibodies and Autonomic Dysfunction in Autoimmune Rheumatic Diseases.International journal of molecular sciences · 2020Review
- Bilateral facial paralysis as a rare neurological manifestation of primary Sjögren's syndrome: case-based review.Rheumatology international · 2019Review
- Neuro-Sjögren: Peripheral Neuropathy With Limb Weakness in Sjögren's Syndrome.Frontiers in immunology · 2019Article
- Neurological and Inflammatory Manifestations in Sjögren's Syndrome: The Role of the Kynurenine Metabolic Pathway.International journal of molecular sciences · 2018Review
- T118M Variant of PMP22 Gene Presents with Painful Peripheral Neuropathy and Varying Charcot-Marie-Tooth Features: A Case Series and Review of the Literature.Case reports in genetics · 2018Article
- Neurological manifestations of primary Sjögren's syndrome.Reumatologia · 2018Review
- Epidemiology of neurological manifestations in Sjögren's syndrome: data from the French ASSESS Cohort.RMD open · 2016Article
- Unusual presentation of Sjögren's syndrome.BMJ case reports · 2014Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clinical and electrophysiological signs of peripheral neuropathy were found in 10 of 46 patients (21.7%) with primary Sjögren's syndrome, symmetric polyneuropathy in seven (mainly sensory in five, mainly autonomic in two), sensory neuronopathy in two patients, and mononeuropathy multiplex in one patient. Peripheral neuropathy was the presenting manifestation in five patients (10.9%). Onset of the disease after 50 years was significantly more common in the polyneuropathy group (six of seven) than in non-neuropathic patients with primary Sjögren's syndrome (14 of 36; p = 0.034). No other difference in clinical or laboratory variables between neuropathic and non-neuropathic patients with primary Sjogren's syndrome was found. Neurophysiological study showed variable findings predominantly suggesting an axonopathy. Nerve biopsy showed moderate remyelination and regeneration in four patients, and fibre loss, mainly of large size, in three. Necrotising vasculitis was not seen but alterations of the endoneurial microvessels were prominent.
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