ReviewClinical microbiology reviews1994
Adhesion and its role in the virulence of enteropathogenic Escherichia coli.
Review in Clinical microbiology reviews, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 94 citations in OpenAlex.
- Molecular characterization ofVeterinary world · 2021Article
- Genome evolution and the emergence of pathogenicity in avian Escherichia coli.Nature communications · 2021Article
- Molecular Biology ofToxins · 2020Review
- The Impact of Age and Pathogens Type on the Gut Microbiota in Infants with Diarrhea in Dalian, China.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2020Article
- Persistent diarrhea: still a serious public health problem in developing countries.Current gastroenterology reports · 2013Review
- Action of phosphorylated mannanoligosaccharides on immune and hematological responses and fecal consistency of dogs experimentally infected with enteropathogenic Escherichia coli strains.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2013Article
- Lymphocytic colitis: a clue to bacterial etiology.World journal of gastroenterology · 2005Article
- Complete DNA sequence and structural analysis of the enteropathogenic Escherichia coli adherence factor plasmid.Infection and immunity · 1999Article
- Effects of orally administered epidermal growth factor on enteropathogenic Escherichia coli infection in rabbits.Infection and immunity · 1998Article
- Divergent signal transduction responses to infection with attaching and effacing Escherichia coli.Infection and immunity · 1998Article
- D-lactate production and [14C]succinic acid uptake by adherent and nonadherent Escherichia coli.Infection and immunity · 1998Article
- Diarrheagenic Escherichia coli.Clinical microbiology reviews · 1998Review
- Escherichia coli in settled-dust and air samples collected in residential environments in Mexico City.Applied and environmental microbiology · 1997Article
- Activation of host cell protein kinase C by enteropathogenic Escherichia coli.Infection and immunity · 1997Article
- Detection system for Escherichia coli-specific virulence genes: absence of virulence determinants in B and C strains.Applied and environmental microbiology · 1997Article
- Identification of a family of intimins common to Escherichia coli causing attaching-effacing lesions in rabbits, humans, and swine.Infection and immunity · 1997Article
- Clonal structure and virulence factors in strains of Escherichia coli of the classic serogroup O55.Infection and immunity · 1996Article
- Characteristics of Escherichia coli strains belonging to enteropathogenic E. coli serogroups isolated in Italy from children with diarrhea.Journal of clinical microbiology · 1996Article
- Genotypic and phenotypic characterization of Escherichia coli isolates from dogs manifesting attaching and effacing lesions.Journal of clinical microbiology · 1996Article
- Monoclonal antibodies specific for the bundle-forming pilus of enteropathogenic Escherichia coli.Infection and immunity · 1995Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enteropathogenic Escherichia coli (EPEC) organisms are an important cause of diarrheal disease in young children. The virulence of EPEC is a multifactorial process and involves a number of distinct stages. Initial adherence to intestinal mucosa is mediated by fimbriae which bring about a distinct form of adhesion, localized adhesion. Intimate adhesion of the bacterium to the eukaryotic membrane occurs, resulting in the activation of signal transduction pathways. Microvilli are disrupted and effaced from the apical membrane which then cups around the organism to form pedestal structures, the attaching and effacing lesion. Diarrhea may be produced by alteration of the permeability of the apical membrane and also through a malabsorption mechanism. The pathways involved in the production of the attaching and effacing lesion are described. EPEC organisms were originally thought to belong to a number of distinct serogroups; it is now apparent that many isolates belonging to these serogroups are not pathogenic or belong to other pathogenic groups of E. coli. In addition, isolates falling outside of these serogroups are considered to be true EPEC. The definition of EPEC based on serotyping is inaccurate and should be replaced by methods that specifically detect the virulence properties of EPEC.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.