ReviewCalcified tissue international1994
Coronary arterial calcification as an active process: a new perspective on an old problem.
Review in Calcified tissue international, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 184 citations in OpenAlex.
- Pooled it
- Key regulators of vascular calcification in chronic kidney disease: Hyperphosphatemia, BMP2, and RUNX2.PeerJ · 2024Review
- Induction of cardiomyocyte calcification is dependent on FoxO1/NFATc3/Runx2 signaling.In vitro cellular & developmental biology. Animal · 2021Article
- Gut Microbiome, Functional Food, Atherosclerosis, and Vascular Calcifications-Is There a Missing Link?Microorganisms · 2021Review
- Bone Morphogenetic Protein-2 and Osteopontin Gene Expression in Epicardial Adipose Tissue from Patients with Coronary Artery Disease Is Associated with the Presence of Calcified Atherosclerotic Plaques.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Signaling pathways involved in vascular smooth muscle cell calcification during hyperphosphatemia.Cellular and molecular life sciences : CMLS · 2019Review
- Association of the Inactive Circulating Matrix Gla Protein with Vitamin K Intake, Calcification, Mortality, and Cardiovascular Disease: A Review.International journal of molecular sciences · 2019Review
- Target identification for the diagnosis and intervention of vulnerable atherosclerotic plaques beyondEuropean journal of nuclear medicine and molecular imaging · 2019Article
- Differences in patients and lesion and procedure characteristics depending on the age of the coronary chronic total occlusion.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2019Article
- Genetics of Subclinical Coronary Atherosclerosis.Current genetic medicine reports · 2018Article
- Analysis of coronary arterial calcification components with coronary CT angiography using single-source dual-energy CT with fast tube voltage switching.The international journal of cardiovascular imaging · 2015Article
- Effects of emotional and physiological stress on plaque instability in apolipoprotein E knockout mice.Journal of physiology and biochemistry · 2011Article
- Low bone mineral density is not associated with angiographically determined coronary atherosclerosis in men.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2010Article
- Association of plasma osteopontin levels with coronary calcification evaluated by tomographic coronary calcium scoring.Journal of bone and mineral metabolism · 2009Article
- Lipid peroxidation and decomposition--conflicting roles in plaque vulnerability and stability.Biochimica et biophysica acta · 2008Review
- The link between osteoporosis and cardiovascular disease.Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases · 2008Article
- The immune response is involved in atherosclerotic plaque calcification: could the RANKL/RANK/OPG system be a marker of plaque instability?Clinical & developmental immunology · 2007Review
- Review
- Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo.The Journal of experimental medicine · 2002Article
- Ectopic calcification: gathering hard facts about soft tissue mineralization.The American journal of pathology · 1999Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanism and purpose of coronary atherosclerotic calcification remain unknown. However, evidence reviewed here suggests that calcification is not passive precipitation or adsorption, but instead is organized and regulated. Gla containing proteins and other proteins normally associated with bone metabolism appear to play an important role in this process. A variety of studies are currently in progress in our laboratory which we hope will provide a more comprehensive understanding of processes leading to coronary calcification as well as prognostic data useful in clinical cardiologic practice. A clearer understanding of the nature and significance of coronary calcification may well pave the way toward new interventions to protect myocardium and minimize the morbidity and mortality associated with coronary artery disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.