Trial reportEuropean journal of applied physiology and occupational physiology1994
Indices of free-radical-mediated damage following maximum voluntary eccentric and concentric muscular work.
Trial report in European journal of applied physiology and occupational physiology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.
- Does post-exercise massage treatment reduce delayed onset muscle soreness? A systematic review.British journal of sports medicine · 1998Pooled it
- Whole-body vibration decreases delayed onset muscle soreness following eccentric exercise in elite hockey players: a randomised controlled trial.Journal of orthopaedic surgery and research · 2021Trial
- Effects of dietary supplementation with vitamins C and E on muscle function during and after eccentric contractions in humans.European journal of applied physiology · 2004Trial
- Eccentric exercise, isokinetic muscle torque and delayed onset muscle soreness: the role of reactive oxygen species.European journal of applied physiology · 2004Trial
- Chronological effects of non-steroidal anti-inflammatory drug therapy on oxidative stress and antioxidant status in patients with rheumatoid arthritis.Clinical rheumatology · 2021Article
- To Compare the Effect of Vibration Therapy and Massage in Prevention of Delayed Onset Muscle Soreness (DOMS).Journal of clinical and diagnostic research : JCDR · 2014Article
- Oxidative stress and nitrite dynamics under maximal load in elite athletes: relation to sport type.Molecular and cellular biochemistry · 2011Article
- Physical exercise increases mitochondrial function and reduces oxidative damage in skeletal muscle.European journal of applied physiology · 2009Article
- Acute exercise and oxidative stress: a 30 year history.Dynamic medicine : DM · 2009Article
- The effect of muscle-damaging exercise on blood and skeletal muscle oxidative stress: magnitude and time-course considerations.Sports medicine (Auckland, N.Z.) · 2008Review
- Effects of different resistance exercise protocols on nitric oxide, lipid peroxidation and creatine kinase activity in sedentary males.Journal of sports science & medicine · 2007Article
- Vitamin C and e supplementation effects in professional soccer players under regular training.Journal of the International Society of Sports Nutrition · 2006Article
- Relationship between oxidative stress in muscle tissue and weight-lifting-induced muscle damage.Pflugers Archiv : European journal of physiology · 2006Article
- Oxidative stress : relationship with exercise and training.Sports medicine (Auckland, N.Z.) · 2006Review
- The effects of antioxidant vitamin supplementation on resistance exercise induced lipid peroxidation in trained and untrained participants.Lipids in health and disease · 2004Article
- Neuromuscular function after exercise-induced muscle damage: theoretical and applied implications.Sports medicine (Auckland, N.Z.) · 2004Review
- Plasma antioxidant status and cell injury after severe physical exercise.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- Evaluation of muscle damage after a rugby match with special reference to tackle plays.British journal of sports medicine · 2003Article
- Biochemical aspects of overtraining in endurance sports: a review.Sports medicine (Auckland, N.Z.) · 2002Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study monitored plasma and skeletal muscle markers of free-radical-mediated damage following maximum eccentric and concentric exercise, to examine the potential role of free radicals in exercise-induced muscle damage. Fourteen male volunteers performed either (1) a bout of 70 maximum eccentric and a bout of 70 maximum concentric muscle actions of the forearm flexors (the bouts being separated by 4 weeks; n = 8) or (2) a bout of 80 maximum eccentric and a bout of 80 maximum concentric muscle actions of the knee extensors (the bouts being separated by 1 week; n = 6). Plasma markers of lipid peroxidation, thiobarbituric acid-reactive substances (TBARS) and diene-conjugated compounds (DCC) were monitored in the arm protocol and skeletal muscle markers of oxidative lipid and protein damage, malondialdehyde (MDA) and protein carbonyl derivatives (PCD) respectively, were monitored in the leg protocol. In both protocols, the contralateral limb was used for the second bout and the order of the bouts was randomised between limbs. Repeated measures ANOVA indicated significant changes from baseline following eccentric arm work on the measures of serum creatine kinase activity (P < 0.05), maximum voluntary torque production (P < 0.01) and relaxed arm angle (P < 0.01). Subjective muscle soreness peaked 2 days after eccentric arm work (P < 0.05, Wilcoxon test). However, there were no changes in the plasma levels of TBARS or DCC following the eccentric or concentric arm exercise. Immediately after concentric leg exercise, skeletal muscle PCD concentrations was significantly higher than that observed immediately after eccentric work (P < 0.05)(ABSTRACT TRUNCATED AT 250 WORDS)
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.