Evidence map›Paper›PMID 8052527›Full record

ArticleNucleic acids research1994

Can SINEs: a family of tRNA-derived retroposons specific to the superfamily Canoidea.

D W Coltman, J M Wright

Open access · greenAbstract readComparative Study
In one paragraph

Article in Nucleic acids research, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
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  8. Review
  9. Review
  10. Article
  11. Evolutionary implications of multiple SINE insertions in an intronic region from diverse mammals.Mammalian genome : official journal of the International Mammalian Genome Society · 2005
    Article
  12. Characterization of an abundant short interspersed nuclear element (SINE) present in Canis familiaris.Mammalian genome : official journal of the International Mammalian Genome Society · 1998
    Article
  13. Article
  14. Microsatellites at a common site in the second ORF of L1 elements in mammalian genomes.Mammalian genome : official journal of the International Mammalian Genome Society · 1996
    Article
  15. Article
  16. Article
  17. Article
  18. SINE elements of carnivores.Mammalian genome : official journal of the International Mammalian Genome Society · 1995
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

D W ColtmanDepartment of Biology, Dalhousie University, Halifax, Nova Scotia, Canada.
J M Wright
Dalhousie University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A repetitive element of approximately 200 bp was cloned from harbour seal (Phoca vitulina concolour) genomic DNA. The sequence of the element revealed putative RNA polymerase III control boxes, a poly A tail and direct terminal repeats characteristic of SINEs. Sequence and secondary structural similarities suggest that the SINE is derived from a tRNA, possibly tRNA-alanine. Southern blot analysis indicated that the element is predominately dispersed in unique regions of the seal genome, but may also be present in other repetitive sequences, such as tandemly arrayed satellite DNA. Based on slot-blot hybridization analysis, we estimate that 1.3 x 10(6) copies of the SINE are present in the harbour seal genome; SINE copy number based on the number of clones isolated from a size-selected library, however, is an order of magnitude lower (1-3 x 10(5) copies), an estimate consistent with the abundance of SINEs in other mammalian genomes. Database searches found similar sequences have been isolated from dog (Canis familiaris) and mink (Mustela vison). These, and the seal SINE sequences are characterized by an internal CT dinucleotide microsatellite in the tRNA-unrelated region. Hybridization of genomic DNA from representative species of a wide range of mammalian orders to an oligonucleotide (30mer) probe complementary to a conserved region of the SINE confirmed that the element is unique to carnivores of the superfamily Canoidea.

Indexed as

DNA Transposable ElementsRepetitive Sequences, Nucleic AcidRetroviridaeAnimalsBase SequenceBiological EvolutionCloning, MolecularConserved SequenceDNADogsMinkMolecular Sequence DataNucleic Acid ConformationRNA, TransferSeals, EarlessSequence Homology, Nucleic AcidDNADNA Transposable ElementsRNA, Transfer

Identifiers

PMID8052527
PMCPMC308240
OpenAlexW2168245023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.