ArticleThe Journal of cell biology1994
Crowding-induced organization of cytoskeletal elements: II. Dissolution of spontaneously formed filament bundles by capping proteins.
Article in The Journal of cell biology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Micro- and macrorheological properties of actin networks effectively cross-linked by depletion forces.Biophysical journal · 2006Article
- Flexible polymer-induced condensation and bundle formation of DNA and F-actin filaments.Biophysical journal · 2001Article
- Nonideality and the nucleation of sickle hemoglobin.Biophysical journal · 2000Article
- Tracer diffusion through F-actin: effect of filament length and cross-linking.Biophysical journal · 1996Article
- The bundling of actin with polyethylene glycol 8000 in the presence and absence of gelsolin.Biophysical journal · 1996Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Through calculations of molecular packing constraints in crowded solutions, we have previously shown that dispersions of filament forming proteins and soluble proteins can be unstable at physiological concentrations, such that tight bundles of filaments are formed spontaneously, in the absence of any accessory binding proteins. Here we consider the modulation of this phenomenon by capping proteins. The theory predicts that, by shortening the average filament length, capping alleviates the packing problem. As a result, the dispersed isotropic solution is stable over an expanded range of compositions.
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