ArticleProceedings of the National Academy of Sciences of the United States of America1994
Domain structure of a mammalian myosin I beta.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 55 citations in OpenAlex.
- Trial
- In situ quantification of protein binding to the plasma membrane.Biophysical journal · 2015Article
- ER sheet persistence is coupled to myosin 1c-regulated dynamic actin filament arrays.Molecular biology of the cell · 2014Article
- Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus.PloS one · 2013Article
- Functional roles for myosin 1c in cellular signaling pathways.Cellular signalling · 2013Review
- Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles.Molecular biology of the cell · 2012Article
- Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cells.The Journal of cell biology · 2012Article
- Myo1c regulates glucose uptake in mouse skeletal muscle.The Journal of biological chemistry · 2011Article
- Modification of loop 1 affects the nucleotide binding properties of Myo1c, the adaptation motor in the inner ear.Biochemistry · 2010Article
- Calcium sensitivity of the cross-bridge cycle of Myo1c, the adaptation motor in the inner ear.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- The nucleolar channel system of human endometrium is related to endoplasmic reticulum and R-rings.Molecular biology of the cell · 2007Article
- Myosin-1c couples assembling actin to membranes to drive compensatory endocytosis.Developmental cell · 2006Article
- Myosin I and adaptation of mechanical transduction by the inner ear.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2004Review
- Unconventional myosin Myo1c promotes membrane fusion in a regulated exocytic pathway.Molecular and cellular biology · 2004Article
- Identification of the membrane receptor of a class XIV myosin in Toxoplasma gondii.The Journal of cell biology · 2004Article
- Myo1c is designed for the adaptation response in the inner ear.The EMBO journal · 2004Article
- Calmodulin binding to recombinant myosin-1c and myosin-1c IQ peptides.BMC biochemistry · 2002Article
- Myosin-1c interacts with hair-cell receptors through its calmodulin-binding IQ domains.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002Article
- Regulation of free Ca2+ concentration in hair-cell stereocilia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1998Article
- ATPase activity of myosin in hair bundles of the bullfrog's sacculus.Biophysical journal · 1997Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
We have determined the primary structure of a myosin I (called mammalian myosin I beta, MMI beta) from bovine brain and identified its functional domains. The protein was previously purified from brain and adrenal gland. Several constructs were generated and expressed in Escherichia coli as glutathione S-transferase fusion proteins and the recombinant proteins were recognized by monoclonal antibodies that recognize either "head" or "tail" domains of native myosin I. A gel overlay method was used to confirm that calmodulin binds to the consensus calmodulin-binding sequence in MMI beta. Binding assays were used to detect interaction with anionic phospholipid vesicles. We conclude that MMI beta consists of an amino-terminal 80.5-kDa domain that contains the ATP- and actin-binding sites, followed by an 8.5-kDa domain with three calmodulin-binding sequences and a basic 30-kDa carboxyl-terminal tail segment that binds to anionic phospholipids and membranes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.