ArticleJournal of bacteriology1994
Cloning and nucleotide sequences of the genes encoding triose phosphate isomerase, phosphoglycerate mutase, and enolase from Bacillus subtilis.
Article in Journal of bacteriology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 66 citations in OpenAlex.
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- The Ser/Thr protein kinase PrkC imprints phenotypic memory inThe Journal of biological chemistry · 2019Article
- In vitro gene silencing of independent phosphoglycerate mutase (iPGM) in the filarial parasite Brugia malayi.Infectious diseases of poverty · 2013Article
- Article
- The Wolbachia endosymbiont of Brugia malayi has an active phosphoglycerate mutase: a candidate target for anti-filarial therapies.Parasitology research · 2009Article
- Molecular cloning and characterization of a phosphoglycerate mutase gene from Clonorchis sinensis.Parasitology research · 2007Article
- Inducer-modulated cooperative binding of the tetrameric CggR repressor to operator DNA.Biophysical journal · 2007Article
- Cofactor-independent phosphoglycerate mutase is an essential gene in procyclic form Trypanosoma brucei.Parasitology research · 2007Article
- Structure and molecular mechanism of Bacillus anthracis cofactor-independent phosphoglycerate mutase: a crucial enzyme for spores and growing cells of Bacillus species.Biophysical journal · 2007Article
- Comparative secretome analyses of three Bacillus anthracis strains with variant plasmid contents.Infection and immunity · 2005Article
- Salt stress proteins induced in Listeria monocytogenes.Applied and environmental microbiology · 2002Article
- A cofactor-dependent phosphoglycerate mutase homolog from Bacillus stearothermophilus is actually a broad specificity phosphatase.Protein science : a publication of the Protein Society · 2001Article
- Analysis of the function of a putative 2,3-diphosphoglyceric acid-dependent phosphoglycerate mutase from Bacillus subtilis.Journal of bacteriology · 2000Article
- A mutation in the 3-phosphoglycerate kinase gene allows anaerobic growth of Bacillus subtilis in the absence of ResE kinase.Journal of bacteriology · 1999Article
- The use of gene clusters to infer functional coupling.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- A model of the quaternary structure of enolases, based on structural and evolutionary analysis of the octameric enolase from Bacillus subtilis.Journal of protein chemistry · 1998Article
- Archaea and the prokaryote-to-eukaryote transition.Microbiology and molecular biology reviews : MMBR · 1997Review
- A null mutation in the Bacillus subtilis aconitase gene causes a block in Spo0A-phosphate-dependent gene expression.Journal of bacteriology · 1997Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The Bacillus subtilis genes tpi, pgm, and eno, encoding triose phosphate isomerase, phosphoglycerate mutase (PGM), and enolase, respectively, have been cloned and sequenced. These genes are the last three in a large putative operon coding for glycolytic enzymes; the operon includes pgk (coding for phosphoglycerate kinase) followed by tpi, pgm, and eno. The triose phosphate isomerase and enolase from B. subtilis are extremely similar to those from all other species, both eukaryotic and prokaryotic. However, B. subtilis PGM bears no resemblance to mammalian, fungal, or gram-negative bacterial PGMs, which are dependent on 2,3-diphosphoglycerate (DPG) for activity. Instead, B. subtilis PGM, which is DPG independent, is very similar to a DPG-independent PGM from a plant species but differs from the latter in the absolute requirement of B. subtilis PGM for Mn2+. The cloned pgm gene has been used to direct up to 25-fold overexpression of PGM in Escherichia coli; this should facilitate purification of large amounts of this novel Mn(2+)-dependent enzyme. Inactivation of pgm plus eno in B. subtilis resulted in extremely slow growth either on plates or in liquid, but growth of these mutants was enhanced by supplementation of media with malate. However, these mutants were asporogenous with or without malate supplementation.
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