ArticlePflugers Archiv : European journal of physiology1994
Segmental differences along the crypt axis in the response of cell volume to secretagogues or hypotonic medium in the rat colon.
Article in Pflugers Archiv : European journal of physiology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- NKCC1: tales from the dark side of the crypt.The Journal of physiology · 2007Article
- Regulatory volume increase after secretory volume decrease in colonic epithelial cells under muscarinic stimulation.Pflugers Archiv : European journal of physiology · 2004Article
- Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD).The Journal of physiology · 2001Review
- Cyclic AMP-dependent regulation of K+ transport in the rat distal colon.British journal of pharmacology · 1996Article
- Crypt base cells show forskolin-induced Cl- secretion but no cation inward conductance.Pflugers Archiv : European journal of physiology · 1996Article
- The ion conductances of colonic crypts from dexamethasone-treated rats.Pflugers Archiv : European journal of physiology · 1996Article
- A new class of inhibitors of cAMP-mediated Cl- secretion in rabbit colon, acting by the reduction of cAMP-activated K+ conductance.Pflugers Archiv : European journal of physiology · 1995Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
VIP caused a decrease in the diameter of rat colonic crypts. This decrease was followed by a volume increase at the middle and the upper third of the crypt, which finally led to an increase of crypt diameter above the initial control values. At the fundus only a cell shrinkage was observed. The volume increase at the upper parts of the crypt was suppressed by the inhibitor of the Na(+)-K(+)-Cl(-)-cotransporter, furosemide. When crypts were exposed to a hypertonic medium, cell shrinkage was followed by a regulatory volume increase at the middle and the upper third of the crypt but not at the fundus region. These results suggest a gradient in the distribution of the Na(+)-K(+)-Cl(-)-cotransporter along the crypt axis.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.