ArticleThe Journal of physiology1994
Force-velocity relation for frog muscle fibres: effects of moderate fatigue and of intracellular acidification.
Article in The Journal of physiology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 68 citations in OpenAlex.
- The force-velocity relationship of human adductor pollicis muscle during stretch and the effects of fatigue.The Journal of physiology · 2000Trial
- Time-of-day, satellite cells, and velocity collectively influence ex vivo isovelocity force production in mouse extensor digitorum longus muscle.Physiological reports · 2026Article
- From fibre to function: are we accurately representing muscle architecture and performance?Biological reviews of the Cambridge Philosophical Society · 2022Review
- The effects of inorganic phosphate on muscle force development and energetics: challenges in modelling related to experimental uncertainties.Journal of muscle research and cell motility · 2021Article
- Is curvature of the force-velocity relationship affected by oxygen availability? Evidence from studies in ex vivo and in situ rat muscles.Pflugers Archiv : European journal of physiology · 2020Article
- On the Shape of the Force-Velocity Relationship in Skeletal Muscles: The Linear, the Hyperbolic, and the Double-Hyperbolic.Frontiers in physiology · 2019Review
- Intramuscular stimulation of tibialis anterior in human subjects: the effects of discharge variability on force production and fatigue.Physiological reports · 2017Article
- Ca++-sensitizing mutations in troponin, P(i), and 2-deoxyATP alter the depressive effect of acidosis on regulated thin-filament velocity.Journal of applied physiology (Bethesda, Md. : 1985) · 2014Article
- Millisecond-scale biochemical response to change in strain.Biophysical journal · 2011Article
- Unconstrained three-dimensional reaching in rhesus monkeys.Experimental brain research · 2011Article
- Changes in the force-velocity relationship of fatigued muscle: implications for power production and possible causes.The Journal of physiology · 2010Review
- Change in contractile properties of human muscle in relationship to the loss of power and slowing of relaxation seen with fatigue.The Journal of physiology · 2006Article
- The mechanism of the force response to stretch in human skinned muscle fibres with different myosin isoforms.The Journal of physiology · 2004Article
- Effects of fatigue on the catchlike property in a turtle hindlimb muscle.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2003Article
- Static and dynamic x-ray diffraction recordings from living mammalian and amphibian skeletal muscles.Biophysical journal · 2003Article
- Force/velocity curves of fast oxidative and fast glycolytic parts of rat medial gastrocnemius muscle vary for concentric but not eccentric activity.Pflugers Archiv : European journal of physiology · 2003Article
- Changes in the maximum speed of shortening of frog muscle fibres early in a tetanic contraction and during relaxation.The Journal of physiology · 1998Article
- The biphasic force-velocity relationship in frog muscle fibres and its evaluation in terms of cross-bridge function.The Journal of physiology · 1997Article
- The effect of intracellular pH on contractile function of intact, single fibres of mouse muscle declines with increasing temperature.The Journal of physiology · 1997Article
- Mechanical efficiency and fatigue of fast and slow muscles of the mouse.The Journal of physiology · 1996Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
1. Intact frog single fibres were investigated under control conditions (1 s tetanus every 2, 3 or 5 min) and during moderate fatigue (interval between tetani 15 or 30 s). 2. Fatigue reduced isometric force (P0) by 25.8 +/- 1.6% (S.E.M.; n = 13) and depressed the maximum velocity of shortening (Vmax) by 10.2 +/- 2.2% (n = 13). The force-velocity relation became less curved, a/P0* (see Methods) being increased by 29.5 +/- 8.8% (n = 13). Thus, power was less affected than isometric force or Vmax. 3. The velocity of unloaded shortening (V0), from slack test measurements, was reduced proportionally more than Vmax during fatigue. Under control conditions V0 was larger than Vmax, but during fatigue their values were not significantly different. 4. Stiffness during shortening was reduced during fatigue indicating fewer attached cross-bridges in fatigue. Force was reduced more than stiffness indicating that, on average, there is less force per attached cross-bridge. 5. The force-lengthening velocity relation showed that the ability to resist forces greater than isometric was well preserved in fatigue. 6. Compared with fatigue, intracellular acidification with CO2 produced a smaller reduction in isometric force. However, reduction in Vmax was not significantly different from that in fatigue. These results are consistent with both inorganic phosphate and H+ increasing in fatigue, but only H+ increasing during acidification, and isometric force being reduced by both, Vmax being sensitive only to H+.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.