ArticleGenetics1994
Detection of genetic interference: simulation studies and mouse data.
Article in Genetics, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Recombination and sterility in inversion homo- and heterokaryotypes under a general counting model of chiasma interference.Genetics · 2023Article
- Meiotic, genomic and evolutionary properties of crossover distribution in Drosophila yakuba.PLoS genetics · 2022Article
- The Genomic Landscape of Crossover Interference in the Desert TreeFrontiers in genetics · 2019Article
- The potential of probabilistic graphical models in linkage map construction.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- Article
- Crossover interference in the mouse.Genetics · 2002Article
- Article
- Characterization of human crossover interference.American journal of human genetics · 2000Article
- Simulation of the distribution of parental strains' genomes in RC strains of mice.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- An anchored molecular map of mouse chromosome 6 with an analysis of interference.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- Proportion of genome shared identical by descent by relatives: concept, computation, and applications.American journal of human genetics · 1995Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Genetic chiasma interference occurs when the occurrence of one crossover (or chiasma) influences the probability of another crossover occurring nearby. We investigated, by simulation studies, the power of three statistical methods to detect interference. Neither the traditional three-locus method nor a multiplicative model approach are very powerful, while a multilocus-feasible map function approach is more powerful, particularly as the number of loci increases. We show that the power to detect interference is quite sensitive to the underlying type of interference. When we tested for interference in two mouse data sets (from chromosomes 1 and 12), we found significant evidence of positive interference.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.