ArticleThe Biochemical journal1994
Calcium-induced translocation of annexins to subcellular organelles of human neutrophils.
Article in The Biochemical journal, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 46 citations in OpenAlex.
- Role of S100A8/A9 for Cytokine Secretion, Revealed in Neutrophils Derived from ER-Hoxb8 Progenitors.International journal of molecular sciences · 2021Article
- Annexin A6 contributes to the invasiveness of breast carcinoma cells by influencing the organization and localization of functional focal adhesions.Experimental cell research · 2011Article
- Stimulus-specific defect in the phagocytic pathways of annexin 1 null macrophages.British journal of pharmacology · 2004Article
- Annexin 2 binding to phosphatidylinositol 4,5-bisphosphate on endocytic vesicles is regulated by the stress response pathway.The Journal of biological chemistry · 2004Article
- Identification and subcellular localization of neuronal calcium sensor-1 (NCS-1) in human neutrophils and HL-60 cells.Inflammation · 2003Article
- Translocation of annexin I from cellular membrane to the nuclear membrane in human esophageal squamous cell carcinoma.World journal of gastroenterology · 2003Article
- Modulation of paclitaxel resistance by annexin IV in human cancer cell lines.British journal of cancer · 2000Article
- Article
- Annexin II in exocytosis: catecholamine secretion requires the translocation of p36 to the subplasmalemmal region in chromaffin cells.The Journal of cell biology · 1996Article
- Translocation of annexin I to plasma membranes and phagosomes in human neutrophils upon stimulation with opsonized zymosan: possible role in phagosome function.The Biochemical journal · 1996Article
- Annexins in Paramecium cells. Involvement in site-specific positioning of secretory organelles.Histochemistry and cell biology · 1996Article
- The lysosomal membrane glycoproteins Lamp-1 and Lamp-2 are present in mobilizable organelles, but are absent from the azurophil granules of human neutrophils.The Biochemical journal · 1995Article
- Serum protects against azurophil granule dependent down-regulation of complement receptor type 1 (CR1) on human neutrophils.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 1995Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The annexins are Ca(2+)-regulated, phospholipid-binding proteins which have been suggested to take part in cellular events such as exocytosis. The subcellular localization of annexins in human neutrophils was determined using monoclonal antibodies against annexins I, II, IV and VI and a polyclonal peptide antiserum against an annexin consensus sequence. Several annexins were translocated to the light membrane fraction enriched in plasma membranes and secretory vesicles. Annexins were associated also with the azurophil and specific granules. Whereas annexins I, IV and VI and one unidentified 35 kDa protein translocated to each of the isolated organelles, annexin II, a 66 kDa annexin IV-like protein, and a 38 kDa annexin I-like protein exhibited organelle-related differences in their association with membranes. The 38 kDa annexin associated only with specific granules and the secretory vesicles/plasma membrane but not with azurophil granules. Annexin II and the 66 kDa annexin IV-like protein associated with each of the neutrophil organelles, but the binding to specific granules and secretory vesicles/plasma membrane showed a Ca(2+)-dependency different from that of azurophil granules. This observation suggests that these proteins may contribute to the secretory process in neutrophils.
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