ArticleOccupational and environmental medicine1994
Time to pregnancy and occupational exposure to pesticides in fruit growers in The Netherlands.
Article in Occupational and environmental medicine, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 133 citations in OpenAlex.
- Non-cancer health effects of pesticides: systematic review and implications for family doctors.Canadian family physician Medecin de famille canadien · 2007Pooled it
- Exposure to pesticides and cryptorchidism: geographical evidence of a possible association.Environmental health perspectives · 1996Trial
- Pesticide exposure and the physical and economic health of US crop workers.Applied economic perspectives and policy · 2021Article
- The impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in IVF.Endocrine connections · 2020Review
- Association between peri-conceptional bisphenol A exposure in women and men and time to pregnancy-The HOPE study.Paediatric and perinatal epidemiology · 2019Article
- Pesticide Exposure and Health Problems Among Female Horticulture Workers in Tanzania.Environmental health insights · 2017Review
- Time-to-pregnancy and pregnancy outcomes in a South African population.BMC public health · 2010Article
- Time-to-pregnancy and risk of schizophrenia.Schizophrenia research · 2010Article
- DDT exposure, work in agriculture, and time to pregnancy among farmworkers in California.Journal of occupational and environmental medicine · 2008Article
- Maternal and paternal occupational exposure to agricultural work and the risk of anencephaly.Occupational and environmental medicine · 2006Article
- Pesticide exposure: the hormonal function of the female reproductive system disrupted?Reproductive biology and endocrinology : RB&E · 2006Review
- Time to first pregnancy among women working in agricultural production.International archives of occupational and environmental health · 2005Article
- Exposure to pesticides and heavy work in greenhouses during pregnancy: does it effect birth weight?International archives of occupational and environmental health · 2005Article
- Comparison of sperm counts in two groups of men presenting for infertility investigations 20 years apart.Reproductive medicine and biology · 2004Article
- Spontaneous abortion in spouses of greenhouse workers exposed to pesticides.Environmental health and preventive medicine · 2003Article
- Developmental toxicity of a commercial herbicide mixture in mice: I. Effects on embryo implantation and litter size.Environmental health perspectives · 2002Article
- Reduction in fertility in male greenhouse workers exposed to pesticides.European journal of epidemiology · 2001Article
- Time to pregnancy and exposure to pesticides in Danish farmers. ASCLEPIOS Study Group.Occupational and environmental medicine · 1998Article
- Are long working hours and shiftwork risk factors for subfecundity? A study among couples from southern Thailand.Occupational and environmental medicine · 1998Article
- Normal and atypical butyrylcholinesterases in placental development, function, and malfunction.Cellular and molecular neurobiology · 1997Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAlthough pesticides are regularly used in agriculture, relatively little is known about possible adverse health effects, especially reproductive effects, due to occupational exposure. This explorative study investigates the relation between exposure of the fruit grower to pesticides and fecundability (probability of pregnancy) in a population of fruit growers.
methodsThe analysis is based on self reported data and includes 91 pregnancies during 1978-1990 of 43 couples. Cox' proportional hazards model was used to analyse time to pregnancy after correction for gravidity and consultation with a physician for fertility problems. RESULTS AND
conclusionsApplication of pesticides solely by the owner was associated with a long time to pregnancy, resulting in a fecundability ratio of 0.46 (95% confidence interval (95% CI) 0.28-0.77). Similarly a low spraying velocity (< or = 1.5 hectares/h) resulted in a fecundability ratio of 0.47 (95% CI 0.29-0.76) and is associated with the use of older spraying techniques and tractors without a cabin. These factors were assumed to cause high exposure, which was confirmed by exposure measurements in the field. The effect of high exposure was mainly apparent if the couple had intended to become pregnant in the period from March-November (fecundability ratio 0.42, 95% CI 0.20-0.92). This is the period in which pesticides are applied. Out of the spraying season the effect of a high exposure was absent (fecundability ratio 0.82, 95% CI 0.33-2.02). In the high exposure group 28% of the pregnancies had been preceded by consulting a physician because of fertility problems, compared with 8% in the low exposure group. These findings indicate that an adverse effect of exposure to pesticides on fecundability is likely.
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