ArticleCell biology and toxicology1994
Derivation and characterization of a zebrafish liver cell line.
Article in Cell biology and toxicology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed.
- A dataset on the multi-species and multi-endpoint bioanalytical assessment of environmental samples derived from Swedish wastewater treatment plants.Data in brief · 2026Article
- Amuc_1100 alleviates HFD-induced hepatic lipid accumulation via gut microbiota in zebrafish: insights from the role of intestinal 14-3-3β/α-A.Journal of animal science and biotechnology · 2026Article
- Emerging Frontiers in Zebrafish Embryonic and Adult-Derived Cell Lines.International journal of molecular sciences · 2025Review
- Establishment and Characterization of Hepatocyte Line from Turbot (Scophthalmus maximus L.) and Its Application in the Study of Glucose Metabolism.Marine biotechnology (New York, N.Y.) · 2025Article
- Development, scrutiny, and modulation of transient reporter gene assays of the xenobiotic metabolism pathway in zebrafish hepatocytes.Cell biology and toxicology · 2023Article
- Establishment, Long-Term Maintenance, and Characterization of Primary Liver Cells from Astyanax mexicanus.Current protocols · 2023Article
- Liver-derived cell lines from cavefish Astyanax mexicanus as an in vitro model for studying metabolic adaptation.Scientific reports · 2022Article
- Excess DHA Induces Liver InjuryFrontiers in nutrition · 2022Article
- Article
- DHA Suppresses Hepatic Lipid AccumulationFrontiers in nutrition · 2021Article
- Potentials and pitfalls of transient in vitro reporter bioassays: interference by vector geometry and cytotoxicity in recombinant zebrafish cell lines.Archives of toxicology · 2020Article
- Article
- Development of an oxidative stress in vitro assay in zebrafish (Danio rerio) cell lines.Scientific reports · 2018Article
- Taurine Biosynthesis in a Fish Liver Cell Line (ZFL) Adapted to a Serum-Free Medium.Marine drugs · 2017Article
- Genotoxic potential of selected cytostatic drugs in human and zebrafish cells.Environmental science and pollution research international · 2016Article
- BFCOD activity in fish cell lines and zebrafish embryos and its modulation by chemical ligands of human aryl hydrocarbon and nuclear receptors.Environmental science and pollution research international · 2015Article
- A DN-mda5 transgenic zebrafish model demonstrates that Mda5 plays an important role in snakehead rhabdovirus resistance.Developmental and comparative immunology · 2015Article
- Zebrafish models of human liver development and disease.Comprehensive Physiology · 2013Review
- Article
- Augmenter of liver regeneration (alr) promotes liver outgrowth during zebrafish hepatogenesis.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ZF-L cells were derived from normal adult zebrafish liver, and have been growing in culture for more than 100 generations. The cells were derived in basal nutrient medium supplemented with fetal bovine serum (FBS), trout serum, trout embryo extract, bovine insulin and mouse epidermal growth factor. After 50 generations in culture, optimal growth of the cells was achieved in medium supplemented with FBS (5%) and trout serum (0.5%). ZF-L cells were hypodiploid (modal chromosome number = 46) and exhibited an epithelial morphology. ZF-L cell homogenates exhibited alanine and aspartate aminotransferase, glucose-6-phosphatase and alkaline phosphatase enzyme activities. The cells synthesized and released several proteins into the culture medium, including a 70 kDa protein recognized by anti-bovine serum albumin IgG.
Indexed as
Identifiers
7994634What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.