ReviewExperientia1994
Hsp70 in parasites: as an inducible protective protein and as an antigen.
Review in Experientia, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 78 citations in OpenAlex.
- Polyparasitism in Two-Stranded Dolphins: Multisystem Pathological Alterations and Cellular Responses.Animals : an open access journal from MDPI · 2026Article
- Novel Strategy for In Vitro Validation of Babesia orientalis Heat Shock Proteins Chaperone Activity and Thermostability.Acta parasitologica · 2024Article
- Proteomic Profiling and In Silico Characterization of the Secretome ofPathogens (Basel, Switzerland) · 2022Article
- Proteomic Analysis ofPathogens (Basel, Switzerland) · 2022Article
- A Biological and Immunological Characterization ofInternational journal of molecular sciences · 2020Article
- Comparative Transcriptome Analyses ofFrontiers in microbiology · 2020Article
- B-chromosome effects on Hsp70 gene expression does not occur at transcriptional level in the grasshopper Eyprepocnemis plorans.Molecular genetics and genomics : MGG · 2016Article
- The Hsp70 response of Anguillicola species to host-specific stressors.Parasitology research · 2016Article
- Transcriptome analysis of genes involved in defence response in Polyporus umbellatus with Armillaria mellea infection.Scientific reports · 2015Article
- Proteomic analysis of adult Ascaris suum fluid compartments and secretory products.PLoS neglected tropical diseases · 2014Article
- Comparative proteomics and expression analysis of five genes in Epicauta chinensis larvae from the first to fifth instar.PloS one · 2014Article
- Helminth parasite proteomics: from experimental models to human infections.Parasitology · 2012Review
- M. paratuberculosis Heat Shock Protein 65 and Human Diseases: Bridging Infection and Autoimmunity.Autoimmune diseases · 2012Article
- Identification of the HSP70-II gene in Leishmania braziliensis HSP70 locus: genomic organization and UTRs characterization.Parasites & vectors · 2011Article
- Changes in membrane fluid state and heat shock response cause attenuation of virulence.Journal of bacteriology · 2010Article
- The structural and functional diversity of Hsp70 proteins from Plasmodium falciparum.Protein science : a publication of the Protein Society · 2007Review
- Relationship between heat shock protein levels and infectivity in Trichinella spiralis larvae exposed to different stressors.Parasitology research · 2005Article
- Development of the primer set for the detection of the hsp60 gene in Trichophyton mentagrophytes cDNA.Folia microbiologica · 1999Article
- Heat shock proteins in immune reactions.Folia microbiologica · 1999Review
- A 70-kilodalton recombinant heat shock protein of Candida albicans is highly immunogenic and enhances systemic murine candidiasis.Infection and immunity · 1998Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
The heat shock (HS) response is a general homeostatic mechanism that protects cells and the entire organism from the deleterious effects of environmental stresses. It has been demonstrated that heat shock proteins (HSP) play major roles in many cellular processes, and have a unique role in several areas of cell biology, from chronic degenerative diseases to immunology, from cancer research to interaction between host and parasites. This review deals with the hsp70 gene family and with its protein product, hsp70, as an antigen when pathogens infect humans. Members of HSP have been shown to be major antigens of many pathogenic organisms when they experience a major temperature shift upwards at the onset of infection and become targets for host B and T cells.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.