ArticleJournal of virology1995
Congo red prolongs the incubation period in scrapie-infected hamsters.
Article in Journal of virology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 157 citations in OpenAlex.
- Prions and protein aggregates as pathogens, self-propagating structures, biomarkers, and therapeutic targets.Microbiology and molecular biology reviews : MMBR · 2025Review
- Exploring immunotherapeutic strategies for neurodegenerative diseases: a focus on Huntington's disease and Prion diseases.Acta pharmacologica Sinica · 2025Review
- Prion therapeutics: Lessons from the past.Prion · 2022Review
- The role of prion strain diversity in the development of successful therapeutic treatments.Progress in molecular biology and translational science · 2020Review
- Article
- Pharmacological Agents Targeting the Cellular Prion Protein.Pathogens (Basel, Switzerland) · 2018Review
- A simple in vitro assay for assessing the efficacy, mechanisms and kinetics of anti-prion fibril compounds.Prion · 2018Article
- Developing Therapeutics for PrP Prion Diseases.Cold Spring Harbor perspectives in medicine · 2017Review
- Antiprion Activity of DB772 and Related Monothiophene- and Furan-Based Analogs in a Persistently Infected Ovine Microglia Culture System.Antimicrobial agents and chemotherapy · 2016Article
- Small-molecule theranostic probes: a promising future in neurodegenerative diseases.International journal of cell biology · 2013Review
- Polythiophenes inhibit prion propagation by stabilizing prion protein (PrP) aggregates.The Journal of biological chemistry · 2012Article
- Discovery of a novel, monocationic, small-molecule inhibitor of scrapie prion accumulation in cultured sheep microglia and Rov cells.PloS one · 2012Article
- Diphenylpyrazole-derived compounds increase survival time of mice after prion infection.Antimicrobial agents and chemotherapy · 2011Article
- Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity.Neurotoxicity research · 2011Article
- Article
- Recent advances in prion chemotherapeutics.Infectious disorders drug targets · 2009Review
- Hormesis and medicine.British journal of clinical pharmacology · 2008Review
- Prion strain- and species-dependent effects of antiprion molecules in primary neuronal cultures.Journal of virology · 2007Article
- Mechanistic insights into the cure of prion disease by novel antiprion compounds.Journal of virology · 2007Article
- Novel aspects of prions, their receptor molecules, and innovative approaches for TSE therapy.Cellular and molecular neurobiology · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In scrapie-infected cells, Congo red inhibits both the replication of the infectious agent and accumulation of the protease-resistant form of PrP (PrP-res). In this report, we show that Congo red prolongs the incubation periods of hamsters experimentally infected with two different strains of scrapie.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.