ArticleGenetics1994
Genetic analysis of Dictyostelium slug phototaxis mutants.
Article in Genetics, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
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- Article
- The Parkinson's disease-associated protein DJ-1 plays a positive nonmitochondrial role in endocytosis inDisease models & mechanisms · 2017Article
- Ndufaf5 deficiency in the Dictyostelium model: new roles in autophagy and development.Molecular biology of the cell · 2013Article
- A genetic interaction between NDPK and AMPK in Dictyostelium discoideum that affects motility, growth and development.Naunyn-Schmiedeberg's archives of pharmacology · 2011Article
- Copine A is expressed in prestalk cells and regulates slug phototaxis and thermotaxis in developing Dictyostelium.Development, growth & differentiation · 2011Article
- A Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation.Developmental biology · 2011Article
- Cell type-specific filamin complex regulation by a novel class of HECT ubiquitin ligase is required for normal cell motility and patterning.Development (Cambridge, England) · 2011Article
- Filamin repeat segments required for photosensory signalling in Dictyostelium discoideum.BMC cell biology · 2007Article
- The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles.Genome biology · 2005Article
- Chaperonin 60 and mitochondrial disease in Dictyostelium.Journal of muscle research and cell motility · 2002Article
- Dictyostelium RasD is required for normal phototaxis, but not differentiation.Genes & development · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mapping and complementation analysis with 17 phototaxis mutations has established 11 complementation groups phoA-phoK distributed over six linkage groups. Statistical calculations from the complementation data yielded 17 as the maximum likelihood estimate of the number of pho genes assuming all loci are equally mutable. Most of the phototaxis mutants were found to exhibit bimodal phototaxis and all were found to be impaired in positive thermotaxis supporting convergence of the photosensory and thermosensory pathways. The thermotaxis mutant HPF228 was unaltered in phototaxis suggesting that the mutation in this strain affects a gene product whose site of action is before the convergence of the two pathways. Other phenotypes such as multiple tip formation by aggregates, stumpy fruiting bodies with short or absent stalks and short migration were associated with some pho alleles suggesting multiple biological roles for some gene products important in phototransduction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.