ArticleAnnals of the rheumatic diseases1994
Clinical features and race-specific incidence/prevalence rates of systemic lupus erythematosus in a geographically complete cohort of patients.
Article in Annals of the rheumatic diseases, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 191 citations in OpenAlex.
- Comprehensive Assessment of the Association between FCGRs polymorphisms and the risk of systemic lupus erythematosus: Evidence from a Meta-Analysis.Scientific reports · 2016Pooled it
- Observational
- Recurrent Temporal Infections: The Link to Systemic Lupus Erythematosus.The American journal of case reports · 2023Article
- Gender-Diverse Inclusion in Immunological Research: Benefits to Science and Health.Frontiers in medicine · 2022Review
- Association between systemic lupus erythematosus and lung cancer: results from a pool of cohort studies and Mendelian randomization analysis.Journal of thoracic disease · 2020Article
- Urinary Metals Concentrations and Biomarkers of Autoimmunity among Navajo and Nicaraguan Men.International journal of environmental research and public health · 2020Article
- Coexistent sickle-cell anemia and autoimmune disease in eight children: pitfalls and challenges.Pediatric rheumatology online journal · 2018Article
- Insights Gained From the Study of Pediatric Systemic Lupus Erythematosus.Frontiers in immunology · 2018Review
- Defining biological subsets in systemic lupus erythematosus: progress toward personalized therapy.Pharmaceutical medicine · 2017Article
- Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus.Annals of the rheumatic diseases · 2017Article
- Presentation of SLE in UK primary care using the Clinical Practice Research Datalink.Lupus science & medicine · 2017Article
- The incidence and prevalence of systemic lupus erythematosus in the UK, 1999-2012.Annals of the rheumatic diseases · 2016Article
- Characteristics related to early secondary amenorrhoea and pregnancy among women diagnosed with systemic lupus erythematosus: an analysis using the GOAL study.Lupus science & medicine · 2016Article
- Off-label use of rituximab for systemic lupus erythematosus in Europe.Lupus science & medicine · 2016Article
- Lupus nephritis in Egyptian children: a 16-year experience.Journal of nephrology · 2015Article
- Genetic association of CD247 (CD3ζ) with SLE in a large-scale multiethnic study.Genes and immunity · 2015Article
- Association between mean platelet volume levels and inflammation in SLE patients presented with arthritis.African health sciences · 2014Article
- Decreased ITGAM and FcγRIIIA mRNA expression levels in peripheral blood mononuclear cells from patients with systemic lupus erythematosus.Clinical and experimental medicine · 2014Article
- Association of STAT4 rs7574865 with susceptibility to systemic lupus erythematosus in Iranian population.Inflammation · 2013Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess race-specific incidence and prevalence rates for systemic lupus erythematosus (SLE) using 1991 National Census data and to ascertain the frequency of clinical/laboratory features of a geographically complete cohort of patients with SLE.
methodsMultiple methods of retrieval were used to ascertain SLE patients including screening request cards for immunology investigations. Patients were classified according to the revised ARA criteria. Multiple logistic regression analysis was used to study the effects of age at diagnosis on the frequency of clinical/laboratory SLE features.
resultsThe overall one year period prevalence rate for SLE was 24.7 (age adjusted, 95% CI: 20.7-28.8)/100,000. Highest rates were seen in Afro-Caribbeans (207 (111-302)/100,000), followed by Asians (48.8 (10.5-87.1)/100,000), and then Whites (20.3 (16.6-24.0)/100,000). The mean age at diagnosis of SLE was 40.9 years (range: 11-83) with a mean interval between first definite SLE symptom and diagnosis of 61 months (0-518). In 85% of patients the first definite lupus feature was musculoskeletal and/or cutaneous. In this SLE cohort renal disease (22%) was observed less commonly than in previous studies and the 'classic' butterfly rash was present in only 30% of patients. Malar rash, thrombocytopaenia, positive anti-dsDNA antibodies, hypocomplementaemia (C4), and positive IgG anticardiolipin antibodies were all seen less commonly with increasing age at diagnosis.
conclusionsA closer estimate of the true frequency of clinical/laboratory SLE manifestations is likely from this geographically complete cohort of patients compared with studies that may be skewed by referral patterns.
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