ArticleMolecular and cellular biology1994
RNA editing and mitochondrial genomic organization in the cryptobiid kinetoplastid protozoan Trypanoplasma borreli.
Article in Molecular and cellular biology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 47 citations in OpenAlex.
- Mitochondrial RNA editing inComputational and structural biotechnology journal · 2022Article
- Article
- High throughput sequencing revolution reveals conserved fundamentals of U-indel editing.Wiley interdisciplinary reviews. RNA · 2018Review
- Orientation of DNA Minicircles Balances Density and Topological Complexity in Kinetoplast DNA.PloS one · 2015Article
- Kinetoplast DNA-encoded ribosomal protein S12: a possible functional link between mitochondrial RNA editing and translation in Trypanosoma brucei.RNA biology · 2013Article
- Proteomics and electron microscopic characterization of the unusual mitochondrial ribosome-related 45S complex in Leishmania tarentolae.Molecular and biochemical parasitology · 2007Article
- Unexplained complexity of the mitochondrial genome and transcriptome in kinetoplastid flagellates.Current genetics · 2005Review
- Unique mitochondrial genome structure in diplonemids, the sister group of kinetoplastids.Eukaryotic cell · 2005Article
- Kinetoplast DNA network: evolution of an improbable structure.Eukaryotic cell · 2002Review
- Evolution of RNA editing in trypanosome mitochondria.Proceedings of the National Academy of Sciences of the United States of America · 2000Review
- Mitochondrial minicircles in the free-living bodonid Bodo saltans contain two gRNA gene cassettes and are not found in large networks.RNA (New York, N.Y.) · 2000Article
- RNA editing in the free-living bodonid Bodo saltans.Nucleic acids research · 1998Article
- Pankinetoplast DNA structure in a primitive bodonid flagellate, Cryptobia helicis.The EMBO journal · 1998Article
- U-insertion/deletion Edited Sequence Database.Nucleic acids research · 1998Article
- The mechanism of U insertion/deletion RNA editing in kinetoplastid mitochondria.Nucleic acids research · 1997Review
- RNA editing in kinetoplastid protozoa.Microbiology and molecular biology reviews : MMBR · 1997Review
- The Naegleria genome: a free-living microbial eukaryote lends unique insights into core eukaryotic cell biology.Research in microbiologyReview
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The bodonids and cryptobiids represent an early diverged sister group to the trypanosomatids among the kinetoplastid protozoa. The trypanosome type of uridine insertion-deletion RNA editing was found to occur in the cryptobiid fish parasite Trypanoplasma borreli. A pan-edited ribosomal protein, S12, and a novel 3'- and 5'-edited cytochrome b, in addition to an unedited cytochrome oxidase III gene and an apparently unedited 12S rRNA gene, were found in a 6-kb fragment of the 80- to 90-kb mitochondrial genome. The gene order differs from that in trypanosomatids, as does the organization of putative guide RNA genes; guide RNA-like molecules are transcribed from tandemly repeated 1-kb sequences organized in 200- and 170-kb molecules instead of minicircles. The presence of pan-editing in this lineage is consistent with an ancient evolutionary origin of this process.
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